Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008662839> ?p ?o ?g. }
- W2008662839 endingPage "1138" @default.
- W2008662839 startingPage "1131" @default.
- W2008662839 abstract "A novel method is reported for rapid protein identification by the analysis of tryptic peptides using desorption electrospray ionisation (DESI) coupled with hyphenated ion mobility spectrometry and quadrupole time-of-flight mass spectrometry (IMS/Q-ToF-MS). Confident protein identification is demonstrated for the analysis of tryptically digested bovine serum albumin (BSA), with no sample pre-treatment or clean-up. Electrophoretic ion mobility separation of ions generated by DESI allowed examination of charge-state and mobility distributions for tryptic peptide mixtures. Selective interrogation of singly charged ions allowed isobaric peptide responses to be distinguished, along with a reduction in spectral noise. The mobility-selected singly charged peptide responses were presented as a pseudo-peptide mass fingerprint (p-PMF) for protein database searching. Comparative data are shown for electrospray ionisation (ESI) of the BSA digest, without sample clean-up, from which confident protein identification could not be made. Implications for the robustness of the DESI method, together with potential insights into mechanisms for DESI of proteolytic digests, are discussed." @default.
- W2008662839 created "2016-06-24" @default.
- W2008662839 creator A5015701981 @default.
- W2008662839 creator A5016963277 @default.
- W2008662839 creator A5045624528 @default.
- W2008662839 creator A5071891210 @default.
- W2008662839 creator A5072537555 @default.
- W2008662839 creator A5029531238 @default.
- W2008662839 date "2007-02-23" @default.
- W2008662839 modified "2023-10-09" @default.
- W2008662839 title "Analysis of tryptic peptides using desorption electrospray ionisation combined with ion mobility spectrometry/mass spectrometry" @default.
- W2008662839 cites W1763558376 @default.
- W2008662839 cites W1966620415 @default.
- W2008662839 cites W1966809971 @default.
- W2008662839 cites W1972033409 @default.
- W2008662839 cites W1973753936 @default.
- W2008662839 cites W1974732006 @default.
- W2008662839 cites W1975871554 @default.
- W2008662839 cites W1979380600 @default.
- W2008662839 cites W1979692315 @default.
- W2008662839 cites W1987148386 @default.
- W2008662839 cites W1990153227 @default.
- W2008662839 cites W1992133896 @default.
- W2008662839 cites W1994682434 @default.
- W2008662839 cites W1999657923 @default.
- W2008662839 cites W2002874506 @default.
- W2008662839 cites W2002973726 @default.
- W2008662839 cites W2003022329 @default.
- W2008662839 cites W2004627688 @default.
- W2008662839 cites W2013641105 @default.
- W2008662839 cites W2025228136 @default.
- W2008662839 cites W2037000107 @default.
- W2008662839 cites W2062820649 @default.
- W2008662839 cites W2063250790 @default.
- W2008662839 cites W2068676098 @default.
- W2008662839 cites W2073029999 @default.
- W2008662839 cites W2073292063 @default.
- W2008662839 cites W2076067099 @default.
- W2008662839 cites W2077314417 @default.
- W2008662839 cites W2078420278 @default.
- W2008662839 cites W2083611912 @default.
- W2008662839 cites W2083694264 @default.
- W2008662839 cites W2085735616 @default.
- W2008662839 cites W2088550407 @default.
- W2008662839 cites W2089174539 @default.
- W2008662839 cites W2092612030 @default.
- W2008662839 cites W2098911352 @default.
- W2008662839 cites W2101936201 @default.
- W2008662839 cites W2113889782 @default.
- W2008662839 cites W2142233556 @default.
- W2008662839 cites W2157520165 @default.
- W2008662839 cites W2160659542 @default.
- W2008662839 cites W2163386717 @default.
- W2008662839 cites W2169113064 @default.
- W2008662839 cites W2171344995 @default.
- W2008662839 cites W4362231430 @default.
- W2008662839 cites W2644804608 @default.
- W2008662839 doi "https://doi.org/10.1002/rcm.2941" @default.
- W2008662839 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17318928" @default.
- W2008662839 hasPublicationYear "2007" @default.
- W2008662839 type Work @default.
- W2008662839 sameAs 2008662839 @default.
- W2008662839 citedByCount "51" @default.
- W2008662839 countsByYear W20086628392012 @default.
- W2008662839 countsByYear W20086628392013 @default.
- W2008662839 countsByYear W20086628392014 @default.
- W2008662839 countsByYear W20086628392015 @default.
- W2008662839 countsByYear W20086628392016 @default.
- W2008662839 countsByYear W20086628392017 @default.
- W2008662839 countsByYear W20086628392018 @default.
- W2008662839 countsByYear W20086628392022 @default.
- W2008662839 crossrefType "journal-article" @default.
- W2008662839 hasAuthorship W2008662839A5015701981 @default.
- W2008662839 hasAuthorship W2008662839A5016963277 @default.
- W2008662839 hasAuthorship W2008662839A5029531238 @default.
- W2008662839 hasAuthorship W2008662839A5045624528 @default.
- W2008662839 hasAuthorship W2008662839A5071891210 @default.
- W2008662839 hasAuthorship W2008662839A5072537555 @default.
- W2008662839 hasConcept C10390740 @default.
- W2008662839 hasConcept C112979427 @default.
- W2008662839 hasConcept C113196181 @default.
- W2008662839 hasConcept C13762613 @default.
- W2008662839 hasConcept C145148216 @default.
- W2008662839 hasConcept C15213710 @default.
- W2008662839 hasConcept C153540111 @default.
- W2008662839 hasConcept C162356407 @default.
- W2008662839 hasConcept C167050937 @default.
- W2008662839 hasConcept C178790620 @default.
- W2008662839 hasConcept C185592680 @default.
- W2008662839 hasConcept C194451485 @default.
- W2008662839 hasConcept C198291218 @default.
- W2008662839 hasConcept C202157981 @default.
- W2008662839 hasConcept C2779281246 @default.
- W2008662839 hasConcept C40684141 @default.
- W2008662839 hasConcept C43617362 @default.
- W2008662839 hasConcept C51884965 @default.
- W2008662839 hasConcept C55493867 @default.
- W2008662839 hasConcept C75233609 @default.