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• W2008702561 abstract "Insect metamorphosis is regulated by ecdysteroids, which induce molts, and juvenile hormone (JH), which inhibits metamorphic changes. The molecular action of ecdysteroids has been thoroughly studied, but that of JH is poorly understood, with data currently only being available for holometabolous species, like Drosophila melanogaster and Tribolium castaneum. We studied the function of Krüppel homolog 1 (Kr-h1) in Blattella germanica, a hemimetabolous model. Kr-h1 is a Zn finger transcription factor whose function as transductor of the antimetamorphic action of JH has recently been demonstrated in D. melanogaster and T. castaneum. The RNAi experiments reported herein indicated that Kr-h1 transduces the antimetamorphic action of JH also in B. germanica, thereby suggesting that this role is an ancestral condition that has been conserved in insect evolution from hemimetabolous to holometabolous species." @default.
• W2008702561 created "2016-06-24" @default.
• W2008702561 creator A5024397445 @default.
• W2008702561 creator A5079453445 @default.
• W2008702561 date "2011-11-21" @default.
• W2008702561 modified "2023-09-28" @default.
• W2008702561 title "Conserved repressive function of Krüppel homolog 1 on insect metamorphosis in hemimetabolous and holometabolous species" @default.
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• W2008702561 doi "https://doi.org/10.1038/srep00163" @default.
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