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- W2008706021 abstract "In addition to the previously reported antiinflammatory agents salinamides A and B from the marine isolate Streptomyces sp. CNB-091, three minor peptides are described. Their total structures were established using a combination of spectral and chemical techniques. Revised structures are presented for the bicyclic depsipeptides salinamides A and B on the basis of the analysis of the dansylated salinamide A hydrolysate by chiral capillary electrophoresis. The fermentation yield of salinamide D, which contains a d-valine residue in place of the d-isoleucine moiety in salinamide A, can be dramatically increased 30-fold by supplementing the growth media with l-valine. Salinamides C and E are monocyclic depsipeptides that are likely methylated byproducts of salinamide A biosynthetic intermediates." @default.
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- W2008706021 date "2010-06-14" @default.
- W2008706021 modified "2023-09-22" @default.
- W2008706021 title "ChemInform Abstract: Salinamides, Antiinflammatory Depsipeptides from a Marine Streptomycete." @default.
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- W2008706021 doi "https://doi.org/10.1002/chin.199928230" @default.
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