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• W2008722912 endingPage "1284" @default.
• W2008722912 startingPage "1275" @default.
• W2008722912 abstract "CTCF is a ubiquitous transcription factor that is involved in numerous, seemingly unrelated functions. These functions include, but are not limited to, positive or negative regulation of transcription, enhancer-blocking activities at developmentally regulated gene clusters and at imprinted loci, and X-chromosome inactivation. Here, we review recent data acquired with state-of-the-art technologies that illuminate possible mechanisms behind the diversity of CTCF functions. CTCF interacts with numerous protein partners, including cohesin, nucleophosmin, PARP1, Yy1 and RNA polymerase II. We propose that CTCF interacts with one or two different partners according to the biological context, applying the Roman principle of governance, `divide and rule' (divide et impera)." @default.
• W2008722912 created "2016-06-24" @default.
• W2008722912 creator A5009701723 @default.
• W2008722912 creator A5060112815 @default.
• W2008722912 date "2009-05-01" @default.
• W2008722912 modified "2023-09-25" @default.
• W2008722912 title "CTCF and its protein partners: divide and rule?" @default.
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• W2008722912 doi "https://doi.org/10.1242/jcs.039990" @default.
• W2008722912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19386894" @default.

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