FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008762308> ?p ?o ?g. }

• W2008762308 endingPage "528" @default.
• W2008762308 startingPage "520" @default.
• W2008762308 abstract "During digestion, dietary proteins cleaved in di and tri-peptides are translocated from the intestinal lumen into the enterocytes via PepT1 (SLC15A1) using an inwardly directed proton electrochemical gradient. The kinetic properties in various PepT1 orthologs (Dicentrarchus labrax, Oryctolagus cuniculus, Danio rerio) have been explored to determine the transport efficiency of different combinations of lysine, methionine, and glycine. Species-specific differences were observed. Lys-Met resulted the best substrate at all tested potentials in sea bass and rabbit PepT1, whereas in the zebrafish transporter all tested dipeptides (except Gly-Lys) elicited similar currents independently on the charge position or amino acid composition. For the sea bass and rabbit PepT1, kinetic parameters, K0.5 and Imax and their ratio, show the importance of the position of the charged lysine in the peptide. The PepT1 transporter of these species has very low affinity for Lys-Lys and Gly-Lys; this reduces the transport efficiency which is instead higher for Lys-Met and Lys-Gly. PepT1 from zebrafish showed relatively high affinity and excellent transport efficiency for Met-Lys and Lys-Met. These data led us to speculate about the structural determinants involved in substrate interaction according to the model proposed for this transporter." @default.
• W2008762308 created "2016-06-24" @default.
• W2008762308 creator A5006481367 @default.
• W2008762308 creator A5049851677 @default.
• W2008762308 creator A5053779739 @default.
• W2008762308 creator A5073024495 @default.
• W2008762308 creator A5077704069 @default.
• W2008762308 creator A5081764501 @default.
• W2008762308 creator A5088400191 @default.
• W2008762308 date "2013-03-01" @default.
• W2008762308 modified "2023-10-01" @default.
• W2008762308 title "Characterization of the transport of lysine-containing dipeptides by PepT1 orthologs expressed in Xenopus laevis oocytes" @default.
• W2008762308 cites W1547809066 @default.
• W2008762308 cites W1579538548 @default.
• W2008762308 cites W169801858 @default.
• W2008762308 cites W1907217156 @default.
• W2008762308 cites W1964967098 @default.
• W2008762308 cites W1966871294 @default.
• W2008762308 cites W1982365908 @default.
• W2008762308 cites W1985592310 @default.
• W2008762308 cites W1992364351 @default.
• W2008762308 cites W1993775682 @default.
• W2008762308 cites W2001877456 @default.
• W2008762308 cites W2015356963 @default.
• W2008762308 cites W2029148102 @default.
• W2008762308 cites W2029530749 @default.
• W2008762308 cites W2030632688 @default.
• W2008762308 cites W2036880458 @default.
• W2008762308 cites W2037198044 @default.
• W2008762308 cites W2050470140 @default.
• W2008762308 cites W2056247020 @default.
• W2008762308 cites W2070400597 @default.
• W2008762308 cites W2071000649 @default.
• W2008762308 cites W2090043825 @default.
• W2008762308 cites W2091405892 @default.
• W2008762308 cites W2092083509 @default.
• W2008762308 cites W2113250101 @default.
• W2008762308 cites W2126151264 @default.
• W2008762308 cites W2131320908 @default.
• W2008762308 cites W2134372752 @default.
• W2008762308 cites W2136499419 @default.
• W2008762308 cites W2139565537 @default.
• W2008762308 cites W2143874428 @default.
• W2008762308 cites W2152976977 @default.
• W2008762308 cites W2156657815 @default.
• W2008762308 cites W2164010784 @default.
• W2008762308 cites W2267299752 @default.
• W2008762308 doi "https://doi.org/10.1016/j.cbpa.2012.12.016" @default.
• W2008762308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23268205" @default.
• W2008762308 hasPublicationYear "2013" @default.
• W2008762308 type Work @default.
• W2008762308 sameAs 2008762308 @default.
• W2008762308 citedByCount "18" @default.
• W2008762308 countsByYear W20087623082013 @default.
• W2008762308 countsByYear W20087623082015 @default.
• W2008762308 countsByYear W20087623082016 @default.
• W2008762308 countsByYear W20087623082018 @default.
• W2008762308 countsByYear W20087623082019 @default.
• W2008762308 countsByYear W20087623082020 @default.
• W2008762308 countsByYear W20087623082021 @default.
• W2008762308 countsByYear W20087623082022 @default.
• W2008762308 countsByYear W20087623082023 @default.
• W2008762308 crossrefType "journal-article" @default.
• W2008762308 hasAuthorship W2008762308A5006481367 @default.
• W2008762308 hasAuthorship W2008762308A5049851677 @default.
• W2008762308 hasAuthorship W2008762308A5053779739 @default.
• W2008762308 hasAuthorship W2008762308A5073024495 @default.
• W2008762308 hasAuthorship W2008762308A5077704069 @default.
• W2008762308 hasAuthorship W2008762308A5081764501 @default.
• W2008762308 hasAuthorship W2008762308A5088400191 @default.
• W2008762308 hasBestOaLocation W20087623082 @default.
• W2008762308 hasConcept C104317684 @default.
• W2008762308 hasConcept C149011108 @default.
• W2008762308 hasConcept C185592680 @default.
• W2008762308 hasConcept C2776016237 @default.
• W2008762308 hasConcept C2776445371 @default.
• W2008762308 hasConcept C2776878037 @default.
• W2008762308 hasConcept C2779281246 @default.
• W2008762308 hasConcept C2779535977 @default.
• W2008762308 hasConcept C2780384893 @default.
• W2008762308 hasConcept C2780912031 @default.
• W2008762308 hasConcept C2909208804 @default.
• W2008762308 hasConcept C505870484 @default.
• W2008762308 hasConcept C515207424 @default.
• W2008762308 hasConcept C55493867 @default.
• W2008762308 hasConcept C86803240 @default.
• W2008762308 hasConceptScore W2008762308C104317684 @default.
• W2008762308 hasConceptScore W2008762308C149011108 @default.
• W2008762308 hasConceptScore W2008762308C185592680 @default.
• W2008762308 hasConceptScore W2008762308C2776016237 @default.
• W2008762308 hasConceptScore W2008762308C2776445371 @default.
• W2008762308 hasConceptScore W2008762308C2776878037 @default.
• W2008762308 hasConceptScore W2008762308C2779281246 @default.
• W2008762308 hasConceptScore W2008762308C2779535977 @default.
• W2008762308 hasConceptScore W2008762308C2780384893 @default.
• W2008762308 hasConceptScore W2008762308C2780912031 @default.
• W2008762308 hasConceptScore W2008762308C2909208804 @default.
• W2008762308 hasConceptScore W2008762308C505870484 @default.

• next