FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008773357> ?p ?o ?g. }

• W2008773357 endingPage "938" @default.
• W2008773357 startingPage "931" @default.
• W2008773357 abstract "The effects of digitalis on retrograde conduction and refractoriness of the His-Purkinje system, ventricular myocardium and reentry within the His-Purkinje system were studied in 17 patients using the ventricular extrastimulus (V2) technique. Studies were performed, before and 30 minutes after intravenous administration of ouabain, 0.01 mg/kg. After treatment with ouabain, there was a significant decrease in the functional refractory period (266 ± 19 to 254 ± 18 msec, P < 0.001), relative refractory period (253 ± 17 to 240 ± 16 msec, P < 0.001) and effective refractory period (242 ± 23 to 231 ± 24 msec, P < 0.005) of the ventricular muscle. In contrast, there was no significant change in retrograde His-Purkinje conduction and refractoriness. The phenomenon of reentry within the His-Purkinje system characterized by the reentrant beat (V3) at critical retrograde conduction delays in the His-Purkinje system (V2-H2) within a narrow range of V1–V2 intervals was seen in 10 of 17 patients. Ouabain increased and shifted to the left the zone of reentry within the His-Purkinje system in 7 of 10 patients (36 ± 23 to 55 ± 23 msec, P < 0.001) and decreased it by 10 to 30 msec in the remaining 3 patients. The critical V2-H2 (186 ± 29 to 193 ± 27 msec, difference not significant [NS]) and V1–V2 (299 ± 30 to 294 ± 36 msec, NS) intervals for reentry did not significantly change after ouabain. However, the minimal V1–V2 intervals (266 ± 26 to 253 ± 25 msec, P < 0.025) decreased significantly, whereas the maximal V2-H2 intervals (266 ± 40 to 239 ± 37 msec, P < 0.01) increased significantly. Thus, in the intact human heart, digitalis (1) significantly decreased all measures of ventricular myocardial refractoriness, (2) had no significant effect on retrograde conduction and refractoriness of the His-Purkinje system, and (3) widened the zone of reentry within the His-Purkinje system due to shortening of the functional refractory period of the ventricular muscle with attainment of longer V2-H2 delays." @default.
• W2008773357 created "2016-06-24" @default.
• W2008773357 creator A5017771527 @default.
• W2008773357 creator A5023178560 @default.
• W2008773357 creator A5047094670 @default.
• W2008773357 creator A5050564336 @default.
• W2008773357 creator A5068832324 @default.
• W2008773357 creator A5073653423 @default.
• W2008773357 date "1978-12-01" @default.
• W2008773357 modified "2023-10-03" @default.
• W2008773357 title "Effects of digitalis on ventricular myocardial and His-Purkinje refractoriness and reentry in man" @default.
• W2008773357 cites W1966329955 @default.
• W2008773357 cites W1968025410 @default.
• W2008773357 cites W1977857679 @default.
• W2008773357 cites W1979292644 @default.
• W2008773357 cites W1979451239 @default.
• W2008773357 cites W1984374161 @default.
• W2008773357 cites W1988479346 @default.
• W2008773357 cites W1989793815 @default.
• W2008773357 cites W1990998921 @default.
• W2008773357 cites W2001841247 @default.
• W2008773357 cites W2003224737 @default.
• W2008773357 cites W2007706248 @default.
• W2008773357 cites W2015316452 @default.
• W2008773357 cites W2037988659 @default.
• W2008773357 cites W2044189939 @default.
• W2008773357 cites W2067482867 @default.
• W2008773357 cites W2071284948 @default.
• W2008773357 cites W2089123851 @default.
• W2008773357 cites W2094692726 @default.
• W2008773357 cites W2122401350 @default.
• W2008773357 cites W2138319073 @default.
• W2008773357 cites W2148259536 @default.
• W2008773357 cites W2157718002 @default.
• W2008773357 cites W2159732710 @default.
• W2008773357 cites W2171598222 @default.
• W2008773357 cites W2332412999 @default.
• W2008773357 cites W3023737981 @default.
• W2008773357 doi "https://doi.org/10.1016/0002-9149(78)90678-1" @default.
• W2008773357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/727144" @default.
• W2008773357 hasPublicationYear "1978" @default.
• W2008773357 type Work @default.
• W2008773357 sameAs 2008773357 @default.
• W2008773357 citedByCount "21" @default.
• W2008773357 countsByYear W20087733572012 @default.
• W2008773357 countsByYear W20087733572013 @default.
• W2008773357 countsByYear W20087733572020 @default.
• W2008773357 crossrefType "journal-article" @default.
• W2008773357 hasAuthorship W2008773357A5017771527 @default.
• W2008773357 hasAuthorship W2008773357A5023178560 @default.
• W2008773357 hasAuthorship W2008773357A5047094670 @default.
• W2008773357 hasAuthorship W2008773357A5050564336 @default.
• W2008773357 hasAuthorship W2008773357A5068832324 @default.
• W2008773357 hasAuthorship W2008773357A5073653423 @default.
• W2008773357 hasConcept C104397207 @default.
• W2008773357 hasConcept C126322002 @default.
• W2008773357 hasConcept C164705383 @default.
• W2008773357 hasConcept C178790620 @default.
• W2008773357 hasConcept C185263204 @default.
• W2008773357 hasConcept C185592680 @default.
• W2008773357 hasConcept C189327125 @default.
• W2008773357 hasConcept C2776445394 @default.
• W2008773357 hasConcept C2777463368 @default.
• W2008773357 hasConcept C2777720157 @default.
• W2008773357 hasConcept C2778198053 @default.
• W2008773357 hasConcept C2779133857 @default.
• W2008773357 hasConcept C2780040984 @default.
• W2008773357 hasConcept C42219234 @default.
• W2008773357 hasConcept C537181965 @default.
• W2008773357 hasConcept C70616116 @default.
• W2008773357 hasConcept C71924100 @default.
• W2008773357 hasConceptScore W2008773357C104397207 @default.
• W2008773357 hasConceptScore W2008773357C126322002 @default.
• W2008773357 hasConceptScore W2008773357C164705383 @default.
• W2008773357 hasConceptScore W2008773357C178790620 @default.
• W2008773357 hasConceptScore W2008773357C185263204 @default.
• W2008773357 hasConceptScore W2008773357C185592680 @default.
• W2008773357 hasConceptScore W2008773357C189327125 @default.
• W2008773357 hasConceptScore W2008773357C2776445394 @default.
• W2008773357 hasConceptScore W2008773357C2777463368 @default.
• W2008773357 hasConceptScore W2008773357C2777720157 @default.
• W2008773357 hasConceptScore W2008773357C2778198053 @default.
• W2008773357 hasConceptScore W2008773357C2779133857 @default.
• W2008773357 hasConceptScore W2008773357C2780040984 @default.
• W2008773357 hasConceptScore W2008773357C42219234 @default.
• W2008773357 hasConceptScore W2008773357C537181965 @default.
• W2008773357 hasConceptScore W2008773357C70616116 @default.
• W2008773357 hasConceptScore W2008773357C71924100 @default.
• W2008773357 hasIssue "6" @default.
• W2008773357 hasLocation W20087733571 @default.
• W2008773357 hasLocation W20087733572 @default.
• W2008773357 hasOpenAccess W2008773357 @default.
• W2008773357 hasPrimaryLocation W20087733571 @default.
• W2008773357 hasRelatedWork W1957800279 @default.
• W2008773357 hasRelatedWork W2008773357 @default.
• W2008773357 hasRelatedWork W2060998212 @default.
• W2008773357 hasRelatedWork W2070541768 @default.
• W2008773357 hasRelatedWork W2080417338 @default.

• next