FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008774671> ?p ?o ?g. }

• W2008774671 endingPage "591" @default.
• W2008774671 startingPage "587" @default.
• W2008774671 abstract "In this study, we selected gelatin as ECM (extracellular matrix) to support differentiation of mES (mouse embryonic stem) cells into TE (trophectoderm), as gelatin was less expensive and widely used. We found that 0.2% and 1.5% gelatin were the suitable concentrations to induce TE differentiation by means of detecting Cdx2 expression using real-time PCR. Moreover, about 15% cells were positive for Cdx2 staining after 6 days differentiation. We discovered that the expressions of specific markers for TE, such as Cdx2, Eomes, Hand1 and Esx1 were prominently increased after gelatin induction. Meanwhile, the expression of Oct4 was significantly decreased. We also found that inhibition of the BMP (bone morphogenetic protein) signalling by Noggin could promote mES cells differentiation into TE, whereas inhibition of the Wnt signalling by Dkk1 had the contrary effect. This could be used as a tool to study the differentiation and function of early trophoblasts as well as further elucidating the molecular mechanism during abnormal placental development." @default.
• W2008774671 created "2016-06-24" @default.
• W2008774671 creator A5001954462 @default.
• W2008774671 creator A5008659525 @default.
• W2008774671 creator A5044180819 @default.
• W2008774671 creator A5066451569 @default.
• W2008774671 date "2011-04-19" @default.
• W2008774671 modified "2023-10-14" @default.
• W2008774671 title "Gelatin induces trophectoderm differentiation of mouse embryonic stem cells" @default.
• W2008774671 cites W1608762409 @default.
• W2008774671 cites W1856781683 @default.
• W2008774671 cites W1894129931 @default.
• W2008774671 cites W1970508192 @default.
• W2008774671 cites W1975751233 @default.
• W2008774671 cites W1994257511 @default.
• W2008774671 cites W2019223731 @default.
• W2008774671 cites W2019750043 @default.
• W2008774671 cites W2040566490 @default.
• W2008774671 cites W2043980237 @default.
• W2008774671 cites W2056089399 @default.
• W2008774671 cites W2067337031 @default.
• W2008774671 cites W2091380345 @default.
• W2008774671 cites W2107277218 @default.
• W2008774671 cites W2119794872 @default.
• W2008774671 cites W2142001424 @default.
• W2008774671 cites W2171996338 @default.
• W2008774671 doi "https://doi.org/10.1042/cbi20100452" @default.
• W2008774671 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21091439" @default.
• W2008774671 hasPublicationYear "2011" @default.
• W2008774671 type Work @default.
• W2008774671 sameAs 2008774671 @default.
• W2008774671 citedByCount "12" @default.
• W2008774671 countsByYear W20087746712012 @default.
• W2008774671 countsByYear W20087746712013 @default.
• W2008774671 countsByYear W20087746712015 @default.
• W2008774671 countsByYear W20087746712016 @default.
• W2008774671 countsByYear W20087746712022 @default.
• W2008774671 countsByYear W20087746712023 @default.
• W2008774671 crossrefType "journal-article" @default.
• W2008774671 hasAuthorship W2008774671A5001954462 @default.
• W2008774671 hasAuthorship W2008774671A5008659525 @default.
• W2008774671 hasAuthorship W2008774671A5044180819 @default.
• W2008774671 hasAuthorship W2008774671A5066451569 @default.
• W2008774671 hasConcept C104317684 @default.
• W2008774671 hasConcept C121587040 @default.
• W2008774671 hasConcept C131364181 @default.
• W2008774671 hasConcept C137620995 @default.
• W2008774671 hasConcept C145103041 @default.
• W2008774671 hasConcept C148738053 @default.
• W2008774671 hasConcept C150194340 @default.
• W2008774671 hasConcept C185592680 @default.
• W2008774671 hasConcept C189165786 @default.
• W2008774671 hasConcept C202751555 @default.
• W2008774671 hasConcept C2778761762 @default.
• W2008774671 hasConcept C2778823387 @default.
• W2008774671 hasConcept C28328180 @default.
• W2008774671 hasConcept C30352789 @default.
• W2008774671 hasConcept C31507581 @default.
• W2008774671 hasConcept C55493867 @default.
• W2008774671 hasConcept C62478195 @default.
• W2008774671 hasConcept C86803240 @default.
• W2008774671 hasConcept C95444343 @default.
• W2008774671 hasConceptScore W2008774671C104317684 @default.
• W2008774671 hasConceptScore W2008774671C121587040 @default.
• W2008774671 hasConceptScore W2008774671C131364181 @default.
• W2008774671 hasConceptScore W2008774671C137620995 @default.
• W2008774671 hasConceptScore W2008774671C145103041 @default.
• W2008774671 hasConceptScore W2008774671C148738053 @default.
• W2008774671 hasConceptScore W2008774671C150194340 @default.
• W2008774671 hasConceptScore W2008774671C185592680 @default.
• W2008774671 hasConceptScore W2008774671C189165786 @default.
• W2008774671 hasConceptScore W2008774671C202751555 @default.
• W2008774671 hasConceptScore W2008774671C2778761762 @default.
• W2008774671 hasConceptScore W2008774671C2778823387 @default.
• W2008774671 hasConceptScore W2008774671C28328180 @default.
• W2008774671 hasConceptScore W2008774671C30352789 @default.
• W2008774671 hasConceptScore W2008774671C31507581 @default.
• W2008774671 hasConceptScore W2008774671C55493867 @default.
• W2008774671 hasConceptScore W2008774671C62478195 @default.
• W2008774671 hasConceptScore W2008774671C86803240 @default.
• W2008774671 hasConceptScore W2008774671C95444343 @default.
• W2008774671 hasIssue "6" @default.
• W2008774671 hasLocation W20087746711 @default.
• W2008774671 hasLocation W20087746712 @default.
• W2008774671 hasOpenAccess W2008774671 @default.
• W2008774671 hasPrimaryLocation W20087746711 @default.
• W2008774671 hasRelatedWork W1122451631 @default.
• W2008774671 hasRelatedWork W1998892538 @default.
• W2008774671 hasRelatedWork W2009519731 @default.
• W2008774671 hasRelatedWork W2055308834 @default.
• W2008774671 hasRelatedWork W2060299616 @default.
• W2008774671 hasRelatedWork W2075798186 @default.
• W2008774671 hasRelatedWork W2116949894 @default.
• W2008774671 hasRelatedWork W2159590253 @default.
• W2008774671 hasRelatedWork W2335071524 @default.
• W2008774671 hasRelatedWork W4361258359 @default.
• W2008774671 hasVolume "35" @default.
• W2008774671 isParatext "false" @default.

• next