FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008778834> ?p ?o ?g. }

• W2008778834 endingPage "712" @default.
• W2008778834 startingPage "708" @default.
• W2008778834 abstract "To determine whether pretreatment serum prostate-specific antigen (PSA) levels in newly diagnosed prostate cancer patients can identify a group with a low probability of osseous metastasis and safely eliminate the need for a bone scan as a routine part of the staging evaluation.We retrospectively reviewed 683 patients with prostate cancer between 1990 and 1993. Patients with prior therapy or serum PSA levels obtained longer than 3 months prior to bone scan were excluded. Bone scans were reviewed by two nuclear medicine physicians with a third deciding equivocal cases.Only 6% of 490 evaluable patients had a positive bone scan on initial evaluation. Scans were positive in 0 of 290 (0%) with PSA levels below 10 micrograms/L, 4 of 88 (4.5%) with PSA levels between 10 and 20 micrograms/L, and 24 of 112 (21%) with PSA levels above 20 micrograms/L. Although the risk of a positive bone scan increased with increasing PSA levels, PSA is a poor positive predictor of positive bone scans. The risk of a positive bone scan was 8% (5 of 64 patients) when PSA was between 20 and 50 micrograms/L, and increased to 40% (19 of 48 patients) for PSA levels greater than 50 micrograms/L. In contrast, serum PSA levels below 10 micrograms/L are strong negative predictors of positive bone scans, with no positive scans in 290 patients with PSA levels below 10 micrograms/L. Although the risk of a positive bone scan increased with increasing stage and grade, tumor stage and grade were poor negative predictors of positive bone scans. Up to 4% of patients with clinically confined or well-differentiated to moderately differentiated tumors had positive scans. Scans were positive in 12% of poorly differentiated tumors, but all these patients had PSA levels above 10 micrograms/L.Our data support the elimination of routine bone scintigraphy in patients with newly diagnosed prostate cancer and PSA levels below 10 micrograms/L. Bone scans are indicated when PSA levels are above 10 micrograms/L, or with T3 or poorly differentiated disease." @default.
• W2008778834 created "2016-06-24" @default.
• W2008778834 creator A5017568119 @default.
• W2008778834 creator A5026709562 @default.
• W2008778834 creator A5045545667 @default.
• W2008778834 creator A5046357677 @default.
• W2008778834 creator A5057779103 @default.
• W2008778834 creator A5065506681 @default.
• W2008778834 creator A5078967237 @default.
• W2008778834 date "1996-05-01" @default.
• W2008778834 modified "2023-09-26" @default.
• W2008778834 title "Ability of serum prostate-specific antigen levels to predict normal bone scans in patients with newly diagnosed prostate cancer" @default.
• W2008778834 cites W1258323304 @default.
• W2008778834 cites W166829100 @default.
• W2008778834 cites W195741252 @default.
• W2008778834 cites W1990997944 @default.
• W2008778834 cites W2004195861 @default.
• W2008778834 cites W2053670125 @default.
• W2008778834 cites W2330292521 @default.
• W2008778834 cites W2335679869 @default.
• W2008778834 cites W75092516 @default.
• W2008778834 doi "https://doi.org/10.1016/s0090-4295(96)80016-1" @default.
• W2008778834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8650870" @default.
• W2008778834 hasPublicationYear "1996" @default.
• W2008778834 type Work @default.
• W2008778834 sameAs 2008778834 @default.
• W2008778834 citedByCount "120" @default.
• W2008778834 countsByYear W20087788342012 @default.
• W2008778834 countsByYear W20087788342013 @default.
• W2008778834 countsByYear W20087788342014 @default.
• W2008778834 countsByYear W20087788342015 @default.
• W2008778834 countsByYear W20087788342016 @default.
• W2008778834 countsByYear W20087788342017 @default.
• W2008778834 countsByYear W20087788342018 @default.
• W2008778834 countsByYear W20087788342020 @default.
• W2008778834 countsByYear W20087788342021 @default.
• W2008778834 countsByYear W20087788342022 @default.
• W2008778834 crossrefType "journal-article" @default.
• W2008778834 hasAuthorship W2008778834A5017568119 @default.
• W2008778834 hasAuthorship W2008778834A5026709562 @default.
• W2008778834 hasAuthorship W2008778834A5045545667 @default.
• W2008778834 hasAuthorship W2008778834A5046357677 @default.
• W2008778834 hasAuthorship W2008778834A5057779103 @default.
• W2008778834 hasAuthorship W2008778834A5065506681 @default.
• W2008778834 hasAuthorship W2008778834A5078967237 @default.
• W2008778834 hasConcept C121608353 @default.
• W2008778834 hasConcept C126322002 @default.
• W2008778834 hasConcept C126838900 @default.
• W2008778834 hasConcept C126894567 @default.
• W2008778834 hasConcept C146357865 @default.
• W2008778834 hasConcept C151730666 @default.
• W2008778834 hasConcept C185592680 @default.
• W2008778834 hasConcept C202751555 @default.
• W2008778834 hasConcept C2776235491 @default.
• W2008778834 hasConcept C2777783956 @default.
• W2008778834 hasConcept C2780192828 @default.
• W2008778834 hasConcept C2781406297 @default.
• W2008778834 hasConcept C2989005 @default.
• W2008778834 hasConcept C51296783 @default.
• W2008778834 hasConcept C55493867 @default.
• W2008778834 hasConcept C71924100 @default.
• W2008778834 hasConcept C86803240 @default.
• W2008778834 hasConceptScore W2008778834C121608353 @default.
• W2008778834 hasConceptScore W2008778834C126322002 @default.
• W2008778834 hasConceptScore W2008778834C126838900 @default.
• W2008778834 hasConceptScore W2008778834C126894567 @default.
• W2008778834 hasConceptScore W2008778834C146357865 @default.
• W2008778834 hasConceptScore W2008778834C151730666 @default.
• W2008778834 hasConceptScore W2008778834C185592680 @default.
• W2008778834 hasConceptScore W2008778834C202751555 @default.
• W2008778834 hasConceptScore W2008778834C2776235491 @default.
• W2008778834 hasConceptScore W2008778834C2777783956 @default.
• W2008778834 hasConceptScore W2008778834C2780192828 @default.
• W2008778834 hasConceptScore W2008778834C2781406297 @default.
• W2008778834 hasConceptScore W2008778834C2989005 @default.
• W2008778834 hasConceptScore W2008778834C51296783 @default.
• W2008778834 hasConceptScore W2008778834C55493867 @default.
• W2008778834 hasConceptScore W2008778834C71924100 @default.
• W2008778834 hasConceptScore W2008778834C86803240 @default.
• W2008778834 hasIssue "5" @default.
• W2008778834 hasLocation W20087788341 @default.
• W2008778834 hasLocation W20087788342 @default.
• W2008778834 hasOpenAccess W2008778834 @default.
• W2008778834 hasPrimaryLocation W20087788341 @default.
• W2008778834 hasRelatedWork W1992657261 @default.
• W2008778834 hasRelatedWork W2038565121 @default.
• W2008778834 hasRelatedWork W2148869351 @default.
• W2008778834 hasRelatedWork W2372081072 @default.
• W2008778834 hasRelatedWork W2373651588 @default.
• W2008778834 hasRelatedWork W2897445903 @default.
• W2008778834 hasRelatedWork W2944341298 @default.
• W2008778834 hasRelatedWork W3129209394 @default.
• W2008778834 hasRelatedWork W3163649103 @default.
• W2008778834 hasRelatedWork W4281788288 @default.
• W2008778834 hasVolume "47" @default.
• W2008778834 isParatext "false" @default.
• W2008778834 isRetracted "false" @default.
• W2008778834 magId "2008778834" @default.

• next