FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008781666> ?p ?o ?g. }

• W2008781666 endingPage "1914" @default.
• W2008781666 startingPage "1905" @default.
• W2008781666 abstract "Stimulation of human SH-SY5Y neuroblastoma cells by a muscarinic receptor agonist, carbachol (CCh; 1 mM), elevated levels of free intracellular calcium and subsequently increased the production of reactive oxygen species (ROS). Quinuclidinylbenzilate (QNB) binding increased at 1 h after CCh, but returned back to the control level at 3 h. Production of ROS increased, however, during the 3 h time period. CCh also increased the translocation of protein kinase C (PKC) to the membrane. ROS production was completely blocked by atropine and a PKC inhibitor, Ro 31-8220. These results show that increased ROS production was a result of muscarinic receptor stimulation, and that PKC had an active role in this cellular stimulation. ROS production upon cellular stimulation by CCh was completely inhibited also by superoxide dismutase, and partially by catalase, indicating that the formation of superoxide anion dominated in cholinergic-induced generation of ROS in human neuroblastoma cells. These results also show that muscarinic stimulation causes sustained ROS production in human neuroblastoma cells. The slow increase in ROS production by CCh suggest a stepwise cascade of events leading to oxidative stress with a triggering role of cholinergic muscarinic receptors in this process." @default.
• W2008781666 created "2016-06-24" @default.
• W2008781666 creator A5007256470 @default.
• W2008781666 creator A5025850544 @default.
• W2008781666 creator A5026989366 @default.
• W2008781666 creator A5051278116 @default.
• W2008781666 date "1997-04-01" @default.
• W2008781666 modified "2023-10-18" @default.
• W2008781666 title "Cholinergic-induced production of reactive oxygen species in human neuroblastoma cells" @default.
• W2008781666 cites W1568529372 @default.
• W2008781666 cites W1745534060 @default.
• W2008781666 cites W1765396147 @default.
• W2008781666 cites W1770711785 @default.
• W2008781666 cites W1964018872 @default.
• W2008781666 cites W1964839077 @default.
• W2008781666 cites W1971334092 @default.
• W2008781666 cites W1972362542 @default.
• W2008781666 cites W1973473665 @default.
• W2008781666 cites W1974018894 @default.
• W2008781666 cites W1978348298 @default.
• W2008781666 cites W1978439843 @default.
• W2008781666 cites W1978778326 @default.
• W2008781666 cites W1980166477 @default.
• W2008781666 cites W1987548555 @default.
• W2008781666 cites W1997059788 @default.
• W2008781666 cites W2002175811 @default.
• W2008781666 cites W2004368602 @default.
• W2008781666 cites W2009012421 @default.
• W2008781666 cites W2015776993 @default.
• W2008781666 cites W2016293448 @default.
• W2008781666 cites W2018640222 @default.
• W2008781666 cites W2048064152 @default.
• W2008781666 cites W2050723087 @default.
• W2008781666 cites W2053096735 @default.
• W2008781666 cites W2056408168 @default.
• W2008781666 cites W2057410920 @default.
• W2008781666 cites W2063501717 @default.
• W2008781666 cites W2090739172 @default.
• W2008781666 cites W2104395061 @default.
• W2008781666 cites W2115647540 @default.
• W2008781666 cites W2133451731 @default.
• W2008781666 cites W2155940800 @default.
• W2008781666 cites W2168532677 @default.
• W2008781666 cites W936661021 @default.
• W2008781666 doi "https://doi.org/10.1016/s0024-3205(97)00152-5" @default.
• W2008781666 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9155001" @default.
• W2008781666 hasPublicationYear "1997" @default.
• W2008781666 type Work @default.
• W2008781666 sameAs 2008781666 @default.
• W2008781666 citedByCount "21" @default.
• W2008781666 countsByYear W20087816662019 @default.
• W2008781666 countsByYear W20087816662022 @default.
• W2008781666 crossrefType "journal-article" @default.
• W2008781666 hasAuthorship W2008781666A5007256470 @default.
• W2008781666 hasAuthorship W2008781666A5025850544 @default.
• W2008781666 hasAuthorship W2008781666A5026989366 @default.
• W2008781666 hasAuthorship W2008781666A5051278116 @default.
• W2008781666 hasConcept C116289061 @default.
• W2008781666 hasConcept C126322002 @default.
• W2008781666 hasConcept C134018914 @default.
• W2008781666 hasConcept C170493617 @default.
• W2008781666 hasConcept C181199279 @default.
• W2008781666 hasConcept C185592680 @default.
• W2008781666 hasConcept C195794163 @default.
• W2008781666 hasConcept C22885893 @default.
• W2008781666 hasConcept C24998067 @default.
• W2008781666 hasConcept C2775838275 @default.
• W2008781666 hasConcept C2776151105 @default.
• W2008781666 hasConcept C2777314051 @default.
• W2008781666 hasConcept C2778988552 @default.
• W2008781666 hasConcept C2780795997 @default.
• W2008781666 hasConcept C33789571 @default.
• W2008781666 hasConcept C48349386 @default.
• W2008781666 hasConcept C55493867 @default.
• W2008781666 hasConcept C62478195 @default.
• W2008781666 hasConcept C71924100 @default.
• W2008781666 hasConcept C86803240 @default.
• W2008781666 hasConcept C95444343 @default.
• W2008781666 hasConceptScore W2008781666C116289061 @default.
• W2008781666 hasConceptScore W2008781666C126322002 @default.
• W2008781666 hasConceptScore W2008781666C134018914 @default.
• W2008781666 hasConceptScore W2008781666C170493617 @default.
• W2008781666 hasConceptScore W2008781666C181199279 @default.
• W2008781666 hasConceptScore W2008781666C185592680 @default.
• W2008781666 hasConceptScore W2008781666C195794163 @default.
• W2008781666 hasConceptScore W2008781666C22885893 @default.
• W2008781666 hasConceptScore W2008781666C24998067 @default.
• W2008781666 hasConceptScore W2008781666C2775838275 @default.
• W2008781666 hasConceptScore W2008781666C2776151105 @default.
• W2008781666 hasConceptScore W2008781666C2777314051 @default.
• W2008781666 hasConceptScore W2008781666C2778988552 @default.
• W2008781666 hasConceptScore W2008781666C2780795997 @default.
• W2008781666 hasConceptScore W2008781666C33789571 @default.
• W2008781666 hasConceptScore W2008781666C48349386 @default.
• W2008781666 hasConceptScore W2008781666C55493867 @default.
• W2008781666 hasConceptScore W2008781666C62478195 @default.
• W2008781666 hasConceptScore W2008781666C71924100 @default.
• W2008781666 hasConceptScore W2008781666C86803240 @default.

• next