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- W2008801111 abstract "Uptake of radioactivity by the brain tissue lipids after oral or intravenousadministration of [I-14C]oleic acid to adult rats is described. 1. Oleic acid was isolated from the brains of adult rats 4 h after intravenousadministration of [I-14C]oleic acid albumin complex or 24 h after oral administration. 2. The distribution of the radioactivity showed that 4 h after injection of[I-14C]oleic acid, the brain oleic acid was still highly labeled in the carboxyl carbon(84%) clearly showing direct uptake. Even after 24 h, the brain oleic acid still hadmore than half of the total radioactivity in the carboxyl carbon. 3. In contrast, the radioactivity in the carboxyl carbon (% of total) of oleicacid isolated after administration of [I-14C]acetate was only 30% at the end of a4-h period and further declined to 23% at the end of 24 h. This further indicatesthat the administered oleic acid was predominantly taken up directly without priordegradation to acetate." @default.
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- W2008801111 date "1970-07-01" @default.
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- W2008801111 title "Fatty acid uptake by the brain" @default.
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- W2008801111 doi "https://doi.org/10.1016/0005-2760(70)90169-4" @default.
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