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• W2008801791 abstract "Two convenient synthetic routes to the oxidized guanosine triphosphate lesions spiroiminodihydantoin-2‘-deoxynucleoside-5‘-triphosphate (dSpTP) and guanidinohydantoin-2‘-deoxynucleoside-5‘-triphosphate (dGhTP) are reported. Both two-electron oxidation of 2‘-deoxy-7,8-dihydro-8-oxoguanosine-5‘-triphosphate (dOGTP) using SO4•- generated photolytically from K2S2O8 or four-electron oxidation of 2‘-deoxyguanosine-5‘-triphosphate (dGTP) from singlet oxygen provide either dSpTP or dGhTP at pH 8.0 or 4.4, respectively. Highly purified triphosphates are obtained by ion pair reversed-phase HPLC." @default.
• W2008801791 created "2016-06-24" @default.
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• W2008801791 date "2006-01-28" @default.
• W2008801791 modified "2023-10-10" @default.
• W2008801791 title "Synthesis and Characterization of the Oxidized dGTP Lesions Spiroiminodihydantoin-2‘-deoxynucleoside-5‘- triphosphate and Guanidinohydantoin-2‘-deoxynucleoside-5‘- triphosphate" @default.
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• W2008801791 doi "https://doi.org/10.1021/jo052484t" @default.
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