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- W2008839227 abstract "Sequential aldol condensation of aldehydes with methyl ketones followed by transition metal-catalyzed addition reactions of arylboronic acids to form β-substituted ketones is described. By using the 1,1′-spirobiindane-7,7′-diol (SPINOL)-based phosphite, an asymmetric version of this type of sequential reaction, with up to 92% ee, was also realized. Our study provided an efficient method to access β-substituted ketones and might lead to the development of other sequential/tandem reactions with transition metal-catalyzed addition reactions as the key step." @default.
- W2008839227 created "2016-06-24" @default.
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- W2008839227 date "2011-03-18" @default.
- W2008839227 modified "2023-10-07" @default.
- W2008839227 title "Sequential Aldol Condensation-Transition Metal-Catalyzed Addition Reactions of Aldehydes, Methyl Ketones, and Arylboronic Acids" @default.
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- W2008839227 doi "https://doi.org/10.1021/ol200457q" @default.
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