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- W2008902015 abstract "Normal mouse mammary epithelial cells, isolated from female Balb/c mice, were cultured as multicellular organoids either on or within collagen gel matrices. Cultures were maintained in either serum-free control medium or the same medium conditioned by mammary adipose tissue. A significant proliferative response above that observed in control cultures (2.5-3.5 fold increase) was induced by conditioned medium derived from either mammary fat-pad explants or isolated adipocytes. In addition, scanning electron microscopy revealed epithelial morphology to be preserved in a more in vivo-like state in the conditioned medium. We conclude that diffusible factors derived from the mouse mammary fat pad influence the proliferative activity and morphology of mammary epithelial cells in culture." @default.
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- W2008902015 modified "2023-09-26" @default.
- W2008902015 title "Growth of mouse mammary epithelium in response to serum-free media conditioned by mammary adipose tissue" @default.
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- W2008902015 doi "https://doi.org/10.1016/0309-1651(88)90122-1" @default.
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