FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008920003> ?p ?o ?g. }

• W2008920003 endingPage "374" @default.
• W2008920003 startingPage "367" @default.
• W2008920003 abstract "Modafinil is a non-amphetaminic psychostimulant used therapeutically for sleep and psychiatric disorders. However, some studies indicate that modafinil can have addictive properties. The present study examined whether modafinil can produce behavioral sensitization in mice, an experience and drug-dependent behavioral adaptation, and if individual differences play a role in this process. We further tested context-related factors and cross-sensitization between modafinil and methamphetamine. Important individual differences in the behavioral sensitization of Swiss Albino mice were observed after repeated administration of 50 mg/kg modafinil (Experiment 1), or 1 mg/kg methamphetamine (Experiment 2). Only mice classified as sensitized subgroup developed clear behavioral sensitization to the drugs. After a withdrawal period, mice received challenges of modafinil (Experiment 1), or methamphetamine (Experiment 2) and locomotor activity was evaluated in the activity cages (previous context) and in the open field arena (new context) in order to evaluate the context dependency of behavioral sensitization. The expression of sensitization to modafinil, but not to methamphetamine, was affected by contextual testing conditions, since modafinil-sensitized mice only expressed sensitization in the activity cage, but not in the open field. Subsequently, locomotor cross-sensitization between methamphetamine and modafinil was assessed by challenging modafinil-pretreated mice with 1mg/kg methamphetamine (Experiment 1), and methamphetamine-pretreated mice with 50mg/kg modafinil (Experiment 2). We observed a symmetrical cross-sensitization between the drugs only in those mice that were classified as sensitized subgroup. Our findings indicate that repeated exposure to modafinil induces behavioral sensitization only in some animals by similar neurobiological, but not contextual, mechanisms to those of methamphetamine." @default.
• W2008920003 created "2016-06-24" @default.
• W2008920003 creator A5005464759 @default.
• W2008920003 creator A5034392363 @default.
• W2008920003 creator A5054769537 @default.
• W2008920003 creator A5055189306 @default.
• W2008920003 creator A5075157768 @default.
• W2008920003 date "2012-08-01" @default.
• W2008920003 modified "2023-10-18" @default.
• W2008920003 title "Individual differences are critical in determining modafinil-induced behavioral sensitization and cross-sensitization with methamphetamine in mice" @default.
• W2008920003 cites W1549510435 @default.
• W2008920003 cites W1902584234 @default.
• W2008920003 cites W1966137409 @default.
• W2008920003 cites W1975350287 @default.
• W2008920003 cites W1977916644 @default.
• W2008920003 cites W1980175882 @default.
• W2008920003 cites W1982383406 @default.
• W2008920003 cites W1983869923 @default.
• W2008920003 cites W1985189974 @default.
• W2008920003 cites W1986311142 @default.
• W2008920003 cites W1991173125 @default.
• W2008920003 cites W1999016165 @default.
• W2008920003 cites W2008741725 @default.
• W2008920003 cites W2010993807 @default.
• W2008920003 cites W2016741793 @default.
• W2008920003 cites W2016772251 @default.
• W2008920003 cites W2018682954 @default.
• W2008920003 cites W2033437417 @default.
• W2008920003 cites W2037263419 @default.
• W2008920003 cites W2043632247 @default.
• W2008920003 cites W2046731194 @default.
• W2008920003 cites W2049929041 @default.
• W2008920003 cites W2052985986 @default.
• W2008920003 cites W2055500305 @default.
• W2008920003 cites W2061161259 @default.
• W2008920003 cites W2061344417 @default.
• W2008920003 cites W2068249288 @default.
• W2008920003 cites W2068302359 @default.
• W2008920003 cites W2070287162 @default.
• W2008920003 cites W2075699091 @default.
• W2008920003 cites W2083243707 @default.
• W2008920003 cites W2084616978 @default.
• W2008920003 cites W2093139327 @default.
• W2008920003 cites W2114078455 @default.
• W2008920003 cites W2115600363 @default.
• W2008920003 cites W2119494912 @default.
• W2008920003 cites W2122011624 @default.
• W2008920003 cites W2126292584 @default.
• W2008920003 cites W2135588856 @default.
• W2008920003 cites W2140991283 @default.
• W2008920003 cites W2150223051 @default.
• W2008920003 cites W2150625787 @default.
• W2008920003 cites W2170001413 @default.
• W2008920003 cites W2335584666 @default.
• W2008920003 cites W2346047599 @default.
• W2008920003 cites W4322694663 @default.
• W2008920003 doi "https://doi.org/10.1016/j.bbr.2012.05.023" @default.
• W2008920003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22652394" @default.
• W2008920003 hasPublicationYear "2012" @default.
• W2008920003 type Work @default.
• W2008920003 sameAs 2008920003 @default.
• W2008920003 citedByCount "15" @default.
• W2008920003 countsByYear W20089200032013 @default.
• W2008920003 countsByYear W20089200032014 @default.
• W2008920003 countsByYear W20089200032015 @default.
• W2008920003 countsByYear W20089200032016 @default.
• W2008920003 countsByYear W20089200032017 @default.
• W2008920003 countsByYear W20089200032018 @default.
• W2008920003 countsByYear W20089200032019 @default.
• W2008920003 countsByYear W20089200032020 @default.
• W2008920003 countsByYear W20089200032021 @default.
• W2008920003 crossrefType "journal-article" @default.
• W2008920003 hasAuthorship W2008920003A5005464759 @default.
• W2008920003 hasAuthorship W2008920003A5034392363 @default.
• W2008920003 hasAuthorship W2008920003A5054769537 @default.
• W2008920003 hasAuthorship W2008920003A5055189306 @default.
• W2008920003 hasAuthorship W2008920003A5075157768 @default.
• W2008920003 hasConcept C118552586 @default.
• W2008920003 hasConcept C151730666 @default.
• W2008920003 hasConcept C15744967 @default.
• W2008920003 hasConcept C169760540 @default.
• W2008920003 hasConcept C2776217527 @default.
• W2008920003 hasConcept C2776552330 @default.
• W2008920003 hasConcept C2777193897 @default.
• W2008920003 hasConcept C2779343474 @default.
• W2008920003 hasConcept C2780376393 @default.
• W2008920003 hasConcept C2780714222 @default.
• W2008920003 hasConcept C3019662062 @default.
• W2008920003 hasConcept C48856860 @default.
• W2008920003 hasConcept C513476851 @default.
• W2008920003 hasConcept C71924100 @default.
• W2008920003 hasConcept C86803240 @default.
• W2008920003 hasConcept C98274493 @default.
• W2008920003 hasConceptScore W2008920003C118552586 @default.
• W2008920003 hasConceptScore W2008920003C151730666 @default.
• W2008920003 hasConceptScore W2008920003C15744967 @default.
• W2008920003 hasConceptScore W2008920003C169760540 @default.
• W2008920003 hasConceptScore W2008920003C2776217527 @default.

• next