FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008928567> ?p ?o ?g. }

• W2008928567 endingPage "220" @default.
• W2008928567 startingPage "213" @default.
• W2008928567 abstract "X-ray micro-analysis was carried out on cultured respiratory cells from polyps removed from individuals with and without cystic fibrosis (CF). In a first set of experiments, proper experimental conditions were established. Washing the cells with 300 mmol l-1 mannitol in distilled water was found to give the best removal of the culture medium. The elemental concentrations stabilized in about 10 min after the start of the preincubation. Intracellular [Na] and [Cl] increased slightly with increasing passage number, whereas intracellular [K] decreased. Under resting conditions there were no significant differences in elemental content between CF and control cells, and there were no indications for abnormally high total [Ca] in CF cells. In normal cells, stimulation with a cAMP-analogue resulted in a decrease of cellular [Cl], whereas in CF cells an increase was measured. Exposure of both normal and CF cells to ouabain resulted in decreased [K] and increased [Na] and [Cl] level. The calcium ionophore A23187 had a similar effect on normal cells but did not affect CF cells markedly. Application of amiloride to the apical side of the cells resulted in a decrease of cellular [Na] in CF cells, whereas [Na] in control cells was not affected. The results correspond with what is known about the defective cAMP-regulated transepithelial Cl-transport in CF cells. The effect of the calcium ionophore on cellular electrolyte content is more complicated and may be the result of two separate effects: efflux of Cl- via a Ca(2+)-dependent mechanism and inhibition of the Na(+)-K(+)-ATPase by intracellular Ca2+ ions causing an influx of Na+ and Cl- ions." @default.
• W2008928567 created "2016-06-24" @default.
• W2008928567 creator A5003789234 @default.
• W2008928567 creator A5010557629 @default.
• W2008928567 creator A5029370447 @default.
• W2008928567 creator A5057168768 @default.
• W2008928567 creator A5085821237 @default.
• W2008928567 creator A5089168328 @default.
• W2008928567 date "1992-10-01" @default.
• W2008928567 modified "2023-10-16" @default.
• W2008928567 title "X-ray micro-analysis of cultured respiratory epithelial cells from patients with cystic fibrosis" @default.
• W2008928567 cites W1898655080 @default.
• W2008928567 cites W1967876020 @default.
• W2008928567 cites W1987121472 @default.
• W2008928567 cites W2007053282 @default.
• W2008928567 cites W2012857882 @default.
• W2008928567 cites W2015881103 @default.
• W2008928567 cites W2021906159 @default.
• W2008928567 cites W2028982633 @default.
• W2008928567 cites W2032013293 @default.
• W2008928567 cites W2033969190 @default.
• W2008928567 cites W2038283641 @default.
• W2008928567 cites W2039599894 @default.
• W2008928567 cites W2042305464 @default.
• W2008928567 cites W2051406889 @default.
• W2008928567 cites W2054710759 @default.
• W2008928567 cites W2057474701 @default.
• W2008928567 cites W2085134206 @default.
• W2008928567 cites W2124965102 @default.
• W2008928567 cites W2141710896 @default.
• W2008928567 cites W2144248619 @default.
• W2008928567 cites W2160904263 @default.
• W2008928567 cites W2224716911 @default.
• W2008928567 cites W2317516580 @default.
• W2008928567 cites W2320394900 @default.
• W2008928567 cites W2329733014 @default.
• W2008928567 cites W2339425856 @default.
• W2008928567 cites W2343771724 @default.
• W2008928567 cites W2410214285 @default.
• W2008928567 cites W4212836148 @default.
• W2008928567 doi "https://doi.org/10.1111/j.1748-1716.1992.tb09410.x" @default.
• W2008928567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1332423" @default.
• W2008928567 hasPublicationYear "1992" @default.
• W2008928567 type Work @default.
• W2008928567 sameAs 2008928567 @default.
• W2008928567 citedByCount "24" @default.
• W2008928567 crossrefType "journal-article" @default.
• W2008928567 hasAuthorship W2008928567A5003789234 @default.
• W2008928567 hasAuthorship W2008928567A5010557629 @default.
• W2008928567 hasAuthorship W2008928567A5029370447 @default.
• W2008928567 hasAuthorship W2008928567A5057168768 @default.
• W2008928567 hasAuthorship W2008928567A5085821237 @default.
• W2008928567 hasAuthorship W2008928567A5089168328 @default.
• W2008928567 hasConcept C126322002 @default.
• W2008928567 hasConcept C134018914 @default.
• W2008928567 hasConcept C178790620 @default.
• W2008928567 hasConcept C185592680 @default.
• W2008928567 hasConcept C24998067 @default.
• W2008928567 hasConcept C2776938444 @default.
• W2008928567 hasConcept C2778445172 @default.
• W2008928567 hasConcept C2779014961 @default.
• W2008928567 hasConcept C2779133857 @default.
• W2008928567 hasConcept C2779608910 @default.
• W2008928567 hasConcept C41625074 @default.
• W2008928567 hasConcept C519063684 @default.
• W2008928567 hasConcept C534529494 @default.
• W2008928567 hasConcept C537181965 @default.
• W2008928567 hasConcept C55493867 @default.
• W2008928567 hasConcept C71924100 @default.
• W2008928567 hasConcept C79879829 @default.
• W2008928567 hasConcept C86803240 @default.
• W2008928567 hasConcept C99975950 @default.
• W2008928567 hasConceptScore W2008928567C126322002 @default.
• W2008928567 hasConceptScore W2008928567C134018914 @default.
• W2008928567 hasConceptScore W2008928567C178790620 @default.
• W2008928567 hasConceptScore W2008928567C185592680 @default.
• W2008928567 hasConceptScore W2008928567C24998067 @default.
• W2008928567 hasConceptScore W2008928567C2776938444 @default.
• W2008928567 hasConceptScore W2008928567C2778445172 @default.
• W2008928567 hasConceptScore W2008928567C2779014961 @default.
• W2008928567 hasConceptScore W2008928567C2779133857 @default.
• W2008928567 hasConceptScore W2008928567C2779608910 @default.
• W2008928567 hasConceptScore W2008928567C41625074 @default.
• W2008928567 hasConceptScore W2008928567C519063684 @default.
• W2008928567 hasConceptScore W2008928567C534529494 @default.
• W2008928567 hasConceptScore W2008928567C537181965 @default.
• W2008928567 hasConceptScore W2008928567C55493867 @default.
• W2008928567 hasConceptScore W2008928567C71924100 @default.
• W2008928567 hasConceptScore W2008928567C79879829 @default.
• W2008928567 hasConceptScore W2008928567C86803240 @default.
• W2008928567 hasConceptScore W2008928567C99975950 @default.
• W2008928567 hasIssue "2" @default.
• W2008928567 hasLocation W20089285671 @default.
• W2008928567 hasLocation W20089285672 @default.
• W2008928567 hasOpenAccess W2008928567 @default.
• W2008928567 hasPrimaryLocation W20089285671 @default.
• W2008928567 hasRelatedWork W1975827353 @default.
• W2008928567 hasRelatedWork W2008928567 @default.

• next