FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008970417> ?p ?o ?g. }

• W2008970417 endingPage "400" @default.
• W2008970417 startingPage "395" @default.
• W2008970417 abstract "Objectives: The purpose of this study, conducted on patients with gingivitis and periodontitis, was twofold: to find out the serum and gingival crevicular fluid concentration of ciprofloxacin, which is a common drug used effectively against Actinobacillus actinomycetemcomitans and to determine the effects of ciprofloxacin administration on clinical parameters. Method: A total of 32 adult patients, consisting of 16 subjects with gingivitis and 16 subjects with untreated chronic periodontitis, were included in the study. The subjects were divided into four groups: group I included eight subjects with chronic gingivitis who had not previously received any ciprofloxacin; group II included eight subjects with chronic gingivitis to whom three doses of ciprofloxacin were administered (Siprosan 500 mg) to establish adequate gingival crevicular fluid and serum concentrations of the agent; group III consisted of eight subjects with chronic periodontitis who had not received any ciprofloxacin; group IV included eight subjects with chronic periodontitis to whom three doses of ciprofloxacin were administered to establish adequate gingival crevicular fluid and serum concentrations of the agent. All patients were systemically healthy, free of pain and reported no current medication usage. Each patient was treated with scaling and/or root planing using specific hand instruments under local anesthesia. Gingival index, plaque index and clinical attachment levels of the teeth were used to determine the clinical condition of the subjects and findings were recorded at the beginning, seventh day, 21st day and third month of the study. Serum ciprofloxacin level was measured in venous blood. Approximately 5 ml of venous blood was drawn from subjects in groups II and IV using a standard venipuncture technique. Gingival crevicular fluid samples were sampled from six interproximal sites with six paper strips in the posterior region of upper jaw (excluding third molar) and all gingival crevicular fluid and serum samples were evaluated by high‐performance liquid chromatography. Results: The serum concentrations of ciprofloxacin at the first and 72nd hour were not significantly different in subjects with periodontitis compared to subjects with gingivitis. But the gingival crevicular fluid concentrations of ciprofloxacin at the same hours were significantly high in subjects with periodontitis compared to subjects with gingivitis. Both subjects with gingivitis and periodontitis had significantly higher ciprofloxacin levels in the gingival crevicular fluid than in serum. The application of ciprofloxacin did not have any positive or statistically significant effect upon the clinical parameters of the subjects with gingivitis. On the other hand, a significant decrease in the clinical attachment level scores of the subjects with periodontitis (group IV) was observed compared to group III in the 21st day and third month. Conclusion: According to these results, the use of ciprofloxacin as an alternative drug in subjects with periodontitis but not gingivitis can be recommended. However, long‐term studies are also needed to assess the effects of ciprofloxacin on clinical parameters." @default.
• W2008970417 created "2016-06-24" @default.
• W2008970417 creator A5002366787 @default.
• W2008970417 creator A5035663705 @default.
• W2008970417 creator A5044760727 @default.
• W2008970417 creator A5047864410 @default.
• W2008970417 creator A5074744942 @default.
• W2008970417 creator A5078972809 @default.
• W2008970417 creator A5085035954 @default.
• W2008970417 date "2005-07-06" @default.
• W2008970417 modified "2023-10-16" @default.
• W2008970417 title "The gingival crevicular fluid ciprofloxacin level in subjects with gingivitis and periodontitis, and its effects on clinical parameters" @default.
• W2008970417 cites W1527241626 @default.
• W2008970417 cites W162831375 @default.
• W2008970417 cites W1790944182 @default.
• W2008970417 cites W1862714762 @default.
• W2008970417 cites W1980155912 @default.
• W2008970417 cites W1981269513 @default.
• W2008970417 cites W1991639866 @default.
• W2008970417 cites W1993812003 @default.
• W2008970417 cites W2019094601 @default.
• W2008970417 cites W2019960412 @default.
• W2008970417 cites W2021452074 @default.
• W2008970417 cites W2021792184 @default.
• W2008970417 cites W2032664626 @default.
• W2008970417 cites W2053343967 @default.
• W2008970417 cites W2054068403 @default.
• W2008970417 cites W2068210133 @default.
• W2008970417 cites W2076976609 @default.
• W2008970417 cites W2079692416 @default.
• W2008970417 cites W2084506086 @default.
• W2008970417 cites W2088465233 @default.
• W2008970417 cites W2107228383 @default.
• W2008970417 cites W2109617307 @default.
• W2008970417 cites W2110485692 @default.
• W2008970417 cites W2162676187 @default.
• W2008970417 cites W2163962639 @default.
• W2008970417 cites W2174784305 @default.
• W2008970417 cites W2180757076 @default.
• W2008970417 cites W2980865894 @default.
• W2008970417 cites W39869222 @default.
• W2008970417 cites W4376595571 @default.
• W2008970417 doi "https://doi.org/10.1111/j.1600-0765.2005.00820.x" @default.
• W2008970417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16105092" @default.
• W2008970417 hasPublicationYear "2005" @default.
• W2008970417 type Work @default.
• W2008970417 sameAs 2008970417 @default.
• W2008970417 citedByCount "15" @default.
• W2008970417 countsByYear W20089704172013 @default.
• W2008970417 countsByYear W20089704172014 @default.
• W2008970417 countsByYear W20089704172015 @default.
• W2008970417 countsByYear W20089704172016 @default.
• W2008970417 countsByYear W20089704172018 @default.
• W2008970417 countsByYear W20089704172019 @default.
• W2008970417 countsByYear W20089704172020 @default.
• W2008970417 countsByYear W20089704172022 @default.
• W2008970417 countsByYear W20089704172023 @default.
• W2008970417 crossrefType "journal-article" @default.
• W2008970417 hasAuthorship W2008970417A5002366787 @default.
• W2008970417 hasAuthorship W2008970417A5035663705 @default.
• W2008970417 hasAuthorship W2008970417A5044760727 @default.
• W2008970417 hasAuthorship W2008970417A5047864410 @default.
• W2008970417 hasAuthorship W2008970417A5074744942 @default.
• W2008970417 hasAuthorship W2008970417A5078972809 @default.
• W2008970417 hasAuthorship W2008970417A5085035954 @default.
• W2008970417 hasConcept C126322002 @default.
• W2008970417 hasConcept C199343813 @default.
• W2008970417 hasConcept C2778512257 @default.
• W2008970417 hasConcept C2779337755 @default.
• W2008970417 hasConcept C2780385504 @default.
• W2008970417 hasConcept C2780728835 @default.
• W2008970417 hasConcept C2780791200 @default.
• W2008970417 hasConcept C501593827 @default.
• W2008970417 hasConcept C58747440 @default.
• W2008970417 hasConcept C71924100 @default.
• W2008970417 hasConcept C86803240 @default.
• W2008970417 hasConcept C89423630 @default.
• W2008970417 hasConcept C90924648 @default.
• W2008970417 hasConceptScore W2008970417C126322002 @default.
• W2008970417 hasConceptScore W2008970417C199343813 @default.
• W2008970417 hasConceptScore W2008970417C2778512257 @default.
• W2008970417 hasConceptScore W2008970417C2779337755 @default.
• W2008970417 hasConceptScore W2008970417C2780385504 @default.
• W2008970417 hasConceptScore W2008970417C2780728835 @default.
• W2008970417 hasConceptScore W2008970417C2780791200 @default.
• W2008970417 hasConceptScore W2008970417C501593827 @default.
• W2008970417 hasConceptScore W2008970417C58747440 @default.
• W2008970417 hasConceptScore W2008970417C71924100 @default.
• W2008970417 hasConceptScore W2008970417C86803240 @default.
• W2008970417 hasConceptScore W2008970417C89423630 @default.
• W2008970417 hasConceptScore W2008970417C90924648 @default.
• W2008970417 hasIssue "5" @default.
• W2008970417 hasLocation W20089704171 @default.
• W2008970417 hasLocation W20089704172 @default.
• W2008970417 hasOpenAccess W2008970417 @default.
• W2008970417 hasPrimaryLocation W20089704171 @default.
• W2008970417 hasRelatedWork W1978951446 @default.
• W2008970417 hasRelatedWork W1995361744 @default.

• next