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• W2008972495 abstract "Untreated depression during pregnancy has been associated with increased morbidity and mortality for both mother and child and, as such, optimal treatment strategies are required for this population.There are conflicting data regarding potential risks of prenatal antidepressant treatment.To determine whether prenatal antidepressant exposure is associated with risk for selected adverse pregnancy or delivery outcomes. DATA SOURCES MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, and the Cochrane Library were searched from their start dates to June 30, 2010. STUDY SELECTION English-language studies reporting outcomes associated with pharmacologic treatment during pregnancy were included. We reviewed 3074 abstracts, retrieved 735 articles, and included 23 studies in this meta-analysis.Study design, antidepressant exposure, adjustment for confounders, and study quality were extracted by 2 independent reviewers.There was no significant association between antidepressant medication exposure and spontaneous abortion (odds ratio [OR], 1.47; 95% CI, 0.99 to 2.17; P = .055). Gestational age and preterm delivery were statistically significantly associated with antidepressant exposure (mean difference [MD] [weeks], -0.45; 95% CI, -0.64 to -0.25; P < .001; and OR, 1.55; 95% CI, 1.38 to 1.74; P < .001, respectively), regardless of whether the comparison group consisted of all unexposed mothers or only depressed mothers without antidepressant exposure. Antidepressant exposure during pregnancy was significantly associated with lower birth weight (MD [grams], -74; 95% CI, -117 to -31; P = .001); when this comparison group was limited to depressed mothers without antidepressant exposure, there was no longer a significant association. Antidepressant exposure was significantly associated with lower Apgar scores at 1 and 5 minutes, regardless of whether the comparison group was all mothers or only those who were depressed during pregnancy but not exposed to antidepressants.Although statistically significant associations between antidepressant exposure and pregnancy and delivery outcomes were identified, group differences were small and scores in the exposed group were typically within the normal ranges, indicating the importance of considering clinical significance. Treatment decisions must weigh the effect of untreated maternal depression against the potential adverse effects of antidepressant exposure." @default.
• W2008972495 created "2016-06-24" @default.
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• W2008972495 date "2013-04-01" @default.
• W2008972495 modified "2023-10-16" @default.
• W2008972495 title "Selected Pregnancy and Delivery Outcomes After Exposure to Antidepressant Medication" @default.
• W2008972495 cites W1545880965 @default.
• W2008972495 cites W1836375302 @default.
• W2008972495 cites W1965639081 @default.
• W2008972495 cites W1972980176 @default.
• W2008972495 cites W1975755498 @default.
• W2008972495 cites W1977989261 @default.
• W2008972495 cites W1978564006 @default.
• W2008972495 cites W1979423827 @default.
• W2008972495 cites W1984792866 @default.
• W2008972495 cites W1990919708 @default.
• W2008972495 cites W1991170688 @default.
• W2008972495 cites W1998048384 @default.
• W2008972495 cites W2009797607 @default.
• W2008972495 cites W2009889141 @default.
• W2008972495 cites W2010124031 @default.
• W2008972495 cites W2013822799 @default.
• W2008972495 cites W2015498942 @default.
• W2008972495 cites W2018951506 @default.
• W2008972495 cites W2019056171 @default.
• W2008972495 cites W2019143627 @default.
• W2008972495 cites W2023101127 @default.
• W2008972495 cites W2023976797 @default.
• W2008972495 cites W2024452373 @default.
• W2008972495 cites W2024866535 @default.
• W2008972495 cites W2026128593 @default.
• W2008972495 cites W2027369712 @default.
• W2008972495 cites W2028351587 @default.
• W2008972495 cites W2033585778 @default.
• W2008972495 cites W2033757879 @default.
• W2008972495 cites W2038134130 @default.
• W2008972495 cites W2038598954 @default.
• W2008972495 cites W2040155286 @default.
• W2008972495 cites W2040681266 @default.
• W2008972495 cites W2045082465 @default.
• W2008972495 cites W2045843799 @default.
• W2008972495 cites W2046178543 @default.
• W2008972495 cites W2047139732 @default.
• W2008972495 cites W2048933622 @default.
• W2008972495 cites W2057165640 @default.
• W2008972495 cites W2066454117 @default.
• W2008972495 cites W2072222819 @default.
• W2008972495 cites W2079464356 @default.
• W2008972495 cites W2082717009 @default.
• W2008972495 cites W2085301156 @default.
• W2008972495 cites W2086694416 @default.
• W2008972495 cites W2087403188 @default.
• W2008972495 cites W2094031914 @default.
• W2008972495 cites W2096203250 @default.
• W2008972495 cites W2097538067 @default.
• W2008972495 cites W2101485714 @default.
• W2008972495 cites W2104128554 @default.
• W2008972495 cites W2104428884 @default.
• W2008972495 cites W2107328434 @default.
• W2008972495 cites W2110512960 @default.
• W2008972495 cites W2114200126 @default.
• W2008972495 cites W2114488753 @default.
• W2008972495 cites W2119119176 @default.
• W2008972495 cites W2120112515 @default.
• W2008972495 cites W2121390454 @default.
• W2008972495 cites W2126930838 @default.
• W2008972495 cites W2128302489 @default.
• W2008972495 cites W2135297770 @default.
• W2008972495 cites W2137027390 @default.
• W2008972495 cites W2137077160 @default.
• W2008972495 cites W2141209469 @default.
• W2008972495 cites W2142883783 @default.
• W2008972495 cites W2145127098 @default.
• W2008972495 cites W2146061370 @default.
• W2008972495 cites W2149264570 @default.
• W2008972495 cites W2149373763 @default.
• W2008972495 cites W2150504996 @default.
• W2008972495 cites W2153712846 @default.
• W2008972495 cites W2154599798 @default.
• W2008972495 cites W2154912010 @default.
• W2008972495 cites W2156098321 @default.
• W2008972495 cites W2157181521 @default.
• W2008972495 cites W2157823046 @default.
• W2008972495 cites W2160473344 @default.
• W2008972495 cites W2163093728 @default.
• W2008972495 cites W2164579326 @default.
• W2008972495 cites W2168495021 @default.
• W2008972495 cites W2177099710 @default.

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