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- W2009011346 abstract "Introduction: For men with elevated prostate-specific antigen (PSA), appropriate management after negative prostate biopsy remains controversial. After determining PSA kinetics, subsequent follow-up was considered. Patients and Methods: A total of 115 cases with negative repeat biopsy were followed by evaluating PSA kinetics and ratio of percent free PSA (F/T) and by performing second repeat biopsy. Results: Eighteen cancer cases were diagnosed. Shorter PSA doubling times and faster velocities were found in cancer cases compared with cases without cancer. We observed a clear decrease in F/T among cancer cases. Conclusions: To avoid unnecessary repeat biopsies, cases with a suspicion of cancer after negative biopsy can be divided into two groups: one that requires additional biopsies and one with an average change in PSA of <1 ng/ml/year and no change in F/T, which is recommended for surveillance as stable disease without biopsy over a specified time period." @default.
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- W2009011346 date "2014-01-01" @default.
- W2009011346 modified "2023-09-26" @default.
- W2009011346 title "Management of Men with a Suspicion of Prostate Cancer after Negative Initial Prostate Biopsy Results" @default.
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- W2009011346 doi "https://doi.org/10.1159/000355355" @default.
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