FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009014799> ?p ?o ?g. }

• W2009014799 endingPage "261" @default.
• W2009014799 startingPage "255" @default.
• W2009014799 abstract "In the present study, we sought to evaluate the role of three polymorphisms in the ecNOS (endothelial constitutive nitric oxide synthase) gene in relation to the existence, severity and progression of CAD (coronary artery disease), MI (myocardial infarction) and the occurrence of ischaemia in a predominantly Caucasian population. Patients with CAD (n=760) and age- and sex-matched population-based controls (n=691) were genotyped for the −786T/C, E/D298 and 4a/b polymorphisms. Patients were randomized to pravastatin (40 mg) or placebo. Progression of atherosclerosis was evaluated by sequential angiography. Functionality was assessed by ST segment analysis of ambulant ECGs. The E298 (P=0.003) and 4a (P=0.001) alleles were associated with CAD. Furthermore, E298 (P=0.009) and −786T (P=0.022) alleles were associated with previous MI among patients, predominantly smokers. D/D298 homozygotes, but not −786T/C or 4a/4b mutants, had longer-lasting ischaemia than others (P&lt;0.05). We found no differences in progression of atherosclerosis, irrespective of pravastatin use. We conclude that the E/D298 polymorphism is most consistently associated with CAD, but not with progression of atherosclerosis. The E allele is associated with CAD and MI, whereas the D allele is associated with ischaemia." @default.
• W2009014799 created "2016-06-24" @default.
• W2009014799 creator A5005451442 @default.
• W2009014799 creator A5005806383 @default.
• W2009014799 creator A5006862347 @default.
• W2009014799 creator A5020130906 @default.
• W2009014799 creator A5050757013 @default.
• W2009014799 creator A5051056050 @default.
• W2009014799 creator A5058855272 @default.
• W2009014799 creator A5077848934 @default.
• W2009014799 creator A5087653861 @default.
• W2009014799 creator A5089523236 @default.
• W2009014799 date "2004-08-24" @default.
• W2009014799 modified "2023-10-18" @default.
• W2009014799 title "An integrated evaluation of endothelial constitutive nitric oxide synthase polymorphisms and coronary artery disease in men" @default.
• W2009014799 cites W1570412320 @default.
• W2009014799 cites W1583052190 @default.
• W2009014799 cites W1599633040 @default.
• W2009014799 cites W1900204802 @default.
• W2009014799 cites W1972561326 @default.
• W2009014799 cites W1990425401 @default.
• W2009014799 cites W1991868168 @default.
• W2009014799 cites W1996465975 @default.
• W2009014799 cites W2000979803 @default.
• W2009014799 cites W2001780724 @default.
• W2009014799 cites W2005337337 @default.
• W2009014799 cites W2010013417 @default.
• W2009014799 cites W2017614092 @default.
• W2009014799 cites W2018550467 @default.
• W2009014799 cites W2025749741 @default.
• W2009014799 cites W2028001069 @default.
• W2009014799 cites W2031320620 @default.
• W2009014799 cites W2036787121 @default.
• W2009014799 cites W2040901946 @default.
• W2009014799 cites W2048666582 @default.
• W2009014799 cites W2076795933 @default.
• W2009014799 cites W2078370178 @default.
• W2009014799 cites W2080887783 @default.
• W2009014799 cites W2103790130 @default.
• W2009014799 cites W2105525798 @default.
• W2009014799 cites W2106649681 @default.
• W2009014799 cites W2131275408 @default.
• W2009014799 cites W2131868847 @default.
• W2009014799 cites W2132634618 @default.
• W2009014799 cites W2137586959 @default.
• W2009014799 cites W2146134563 @default.
• W2009014799 cites W2147534219 @default.
• W2009014799 cites W2169182236 @default.
• W2009014799 cites W2267941286 @default.
• W2009014799 cites W2341272418 @default.
• W2009014799 cites W4385996143 @default.
• W2009014799 doi "https://doi.org/10.1042/cs20030360" @default.
• W2009014799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15068395" @default.
• W2009014799 hasPublicationYear "2004" @default.
• W2009014799 type Work @default.
• W2009014799 sameAs 2009014799 @default.
• W2009014799 citedByCount "30" @default.
• W2009014799 countsByYear W20090147992012 @default.
• W2009014799 countsByYear W20090147992013 @default.
• W2009014799 countsByYear W20090147992014 @default.
• W2009014799 countsByYear W20090147992019 @default.
• W2009014799 countsByYear W20090147992023 @default.
• W2009014799 crossrefType "journal-article" @default.
• W2009014799 hasAuthorship W2009014799A5005451442 @default.
• W2009014799 hasAuthorship W2009014799A5005806383 @default.
• W2009014799 hasAuthorship W2009014799A5006862347 @default.
• W2009014799 hasAuthorship W2009014799A5020130906 @default.
• W2009014799 hasAuthorship W2009014799A5050757013 @default.
• W2009014799 hasAuthorship W2009014799A5051056050 @default.
• W2009014799 hasAuthorship W2009014799A5058855272 @default.
• W2009014799 hasAuthorship W2009014799A5077848934 @default.
• W2009014799 hasAuthorship W2009014799A5087653861 @default.
• W2009014799 hasAuthorship W2009014799A5089523236 @default.
• W2009014799 hasConcept C104317684 @default.
• W2009014799 hasConcept C126322002 @default.
• W2009014799 hasConcept C164705383 @default.
• W2009014799 hasConcept C180754005 @default.
• W2009014799 hasConcept C2778163477 @default.
• W2009014799 hasConcept C2778213512 @default.
• W2009014799 hasConcept C2779519902 @default.
• W2009014799 hasConcept C2908647359 @default.
• W2009014799 hasConcept C2991716557 @default.
• W2009014799 hasConcept C500558357 @default.
• W2009014799 hasConcept C54355233 @default.
• W2009014799 hasConcept C71924100 @default.
• W2009014799 hasConcept C86803240 @default.
• W2009014799 hasConcept C99454951 @default.
• W2009014799 hasConceptScore W2009014799C104317684 @default.
• W2009014799 hasConceptScore W2009014799C126322002 @default.
• W2009014799 hasConceptScore W2009014799C164705383 @default.
• W2009014799 hasConceptScore W2009014799C180754005 @default.
• W2009014799 hasConceptScore W2009014799C2778163477 @default.
• W2009014799 hasConceptScore W2009014799C2778213512 @default.
• W2009014799 hasConceptScore W2009014799C2779519902 @default.
• W2009014799 hasConceptScore W2009014799C2908647359 @default.
• W2009014799 hasConceptScore W2009014799C2991716557 @default.
• W2009014799 hasConceptScore W2009014799C500558357 @default.
• W2009014799 hasConceptScore W2009014799C54355233 @default.

• next