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- W2009018781 abstract ". Joy CB, Adams CE, Lawrie SM. Haloperidol versus placebo for schizophrenia. Cochrane Database Syst Rev 2001;(2):CD003082 (latest version 9 Feb 2001). . QUESTION: In patients with schizophrenia, what are the clinical effects of haloperidol compared with placebo?Studies were identified by searching databases including EMBASE/Excerpta Medica (1980 to Feb 1998), Medline (1966 to Feb 1998), PsycLIT (1974 to Feb 1998), and SCISEARCH (1974–98); scanning references of articles; contacting authors; and handsearching high yield journals.Randomised controlled trials (RCTs) were selected if they compared haloperidol (excluding depot forms of the drug*) with placebo in people with schizophrenia or similar, serious, non-affective psychosis. Quasi-randomised studies were excluded.2 reviewers independently assessed the quality of study methods. All reviewers independently extracted data on methods, participants, interventions, and outcomes.20 RCTs (2120 patients) met the selection criteria (sample size range 12–388 patients). …" @default.
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- W2009018781 date "2001-11-01" @default.
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- W2009018781 title "Review: haloperidol is effective for schizophrenia but increases parkinsonism, dystonia, and akathisia" @default.
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- W2009018781 doi "https://doi.org/10.1136/ebmh.4.4.112" @default.
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