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- W2009023085 abstract "A four-component Ugi reaction (Ugi-4CR) utilizing formylphenyl boronic acids under mild condition was developed for the synthesis of arylboronic acid analogs. The reactions were performed in methanol and accelerated by microwave irradiation, which makes this strategy suitable for constructing boronic-containing chemical libraries. Two of the synthesized analogs were found to have cytotoxic activity against HepG2, MDA-MB231, and A549 cancer cell lines, demonstrating the potential application of this approach in developing novel boron-containing pharmaceuticals." @default.
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- W2009023085 date "2014-03-01" @default.
- W2009023085 modified "2023-10-17" @default.
- W2009023085 title "Direct synthesis of the arylboronic acid analogues of phenylglycine via microwave-assisted four-component Ugi reaction" @default.
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- W2009023085 doi "https://doi.org/10.1016/j.tet.2014.01.016" @default.
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