FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009026789> ?p ?o ?g. }

• W2009026789 endingPage "322" @default.
• W2009026789 startingPage "315" @default.
• W2009026789 abstract "Summary. The development of an inhibitor against factor VIII (FVIII) is a serious complication in children with haemophilia A. Immune tolerance induction (ITI) therapy is generally considered to be the best approach to eradicate the inhibitor. In this paper, the low‐dose (≤50 IU kg −1 twice or three times weekly with plasma‐derived factor concentrates) ITI regimen used in Turkey is discussed. This regimen was given to 21 haemophilia A patients with high titer inhibitors. The median age at the beginning of ITI was 9 years and exposure days were 25. The median pre‐ITI historical peak inhibitor titer, and inhibitor titer when ITI started were 80 BU (range 6.0–517), 19.2 BU (range 3.6–515), respectively. Complete immune tolerance was defined as the time at which at least two negative inhibitor assays was obtained with no anamnestic response. Our two cases were not reached in follow‐up period. Immune tolerance could be achieved in 5 of 19 (26.3%) patients within a median time of 6 months. Partial tolerance was obtained in 7 patients while treatment failed in spite of significant decreased inhibitor levels in the other patients. A relapse developed in one immune‐tolerized patient, one year later. The level of inhibitor titer at the beginning of ITI (≤10 BU), the pre‐ITI historical peak inhibitor titer (<50 BU), and the time between the first diagnosis inhibitor to starting ITI (<12 months) were main factors in the success (complete or partial tolerance) of ITI. In conclusion, the outcome of low‐dose ITI protocol was not satisfactory in this retrospective study." @default.
• W2009026789 created "2016-06-24" @default.
• W2009026789 creator A5026686218 @default.
• W2009026789 creator A5038006402 @default.
• W2009026789 creator A5041078773 @default.
• W2009026789 creator A5063357713 @default.
• W2009026789 creator A5069337753 @default.
• W2009026789 creator A5073034245 @default.
• W2009026789 creator A5085306795 @default.
• W2009026789 creator A5090715353 @default.
• W2009026789 date "2007-12-11" @default.
• W2009026789 modified "2023-10-15" @default.
• W2009026789 title "Low-dose immune tolerance induction for paediatric haemophilia patients with factor VIII inhibitors" @default.
• W2009026789 cites W1528709070 @default.
• W2009026789 cites W1921219324 @default.
• W2009026789 cites W1965131675 @default.
• W2009026789 cites W1966674633 @default.
• W2009026789 cites W1998614164 @default.
• W2009026789 cites W1999636421 @default.
• W2009026789 cites W2000807098 @default.
• W2009026789 cites W2001830012 @default.
• W2009026789 cites W2006369594 @default.
• W2009026789 cites W2021047792 @default.
• W2009026789 cites W2023810744 @default.
• W2009026789 cites W2026092907 @default.
• W2009026789 cites W2026384838 @default.
• W2009026789 cites W2028940468 @default.
• W2009026789 cites W2041148634 @default.
• W2009026789 cites W2056634959 @default.
• W2009026789 cites W2077665333 @default.
• W2009026789 cites W2080556377 @default.
• W2009026789 cites W2085667743 @default.
• W2009026789 cites W2095583634 @default.
• W2009026789 cites W2103667265 @default.
• W2009026789 cites W2103793215 @default.
• W2009026789 cites W2108177522 @default.
• W2009026789 cites W2114841273 @default.
• W2009026789 cites W2119212931 @default.
• W2009026789 cites W2156715774 @default.
• W2009026789 cites W2158600991 @default.
• W2009026789 cites W2172269466 @default.
• W2009026789 cites W2412302696 @default.
• W2009026789 cites W2417605240 @default.
• W2009026789 doi "https://doi.org/10.1111/j.1365-2516.2007.01621.x" @default.
• W2009026789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18081830" @default.
• W2009026789 hasPublicationYear "2007" @default.
• W2009026789 type Work @default.
• W2009026789 sameAs 2009026789 @default.
• W2009026789 citedByCount "20" @default.
• W2009026789 countsByYear W20090267892012 @default.
• W2009026789 countsByYear W20090267892014 @default.
• W2009026789 countsByYear W20090267892015 @default.
• W2009026789 countsByYear W20090267892016 @default.
• W2009026789 countsByYear W20090267892019 @default.
• W2009026789 countsByYear W20090267892020 @default.
• W2009026789 countsByYear W20090267892021 @default.
• W2009026789 countsByYear W20090267892022 @default.
• W2009026789 countsByYear W20090267892023 @default.
• W2009026789 crossrefType "journal-article" @default.
• W2009026789 hasAuthorship W2009026789A5026686218 @default.
• W2009026789 hasAuthorship W2009026789A5038006402 @default.
• W2009026789 hasAuthorship W2009026789A5041078773 @default.
• W2009026789 hasAuthorship W2009026789A5063357713 @default.
• W2009026789 hasAuthorship W2009026789A5069337753 @default.
• W2009026789 hasAuthorship W2009026789A5073034245 @default.
• W2009026789 hasAuthorship W2009026789A5085306795 @default.
• W2009026789 hasAuthorship W2009026789A5090715353 @default.
• W2009026789 hasConcept C126322002 @default.
• W2009026789 hasConcept C141071460 @default.
• W2009026789 hasConcept C159654299 @default.
• W2009026789 hasConcept C203014093 @default.
• W2009026789 hasConcept C2777232031 @default.
• W2009026789 hasConcept C2777702733 @default.
• W2009026789 hasConcept C2778385053 @default.
• W2009026789 hasConcept C2781413609 @default.
• W2009026789 hasConcept C32611913 @default.
• W2009026789 hasConcept C71924100 @default.
• W2009026789 hasConcept C8891405 @default.
• W2009026789 hasConcept C90924648 @default.
• W2009026789 hasConceptScore W2009026789C126322002 @default.
• W2009026789 hasConceptScore W2009026789C141071460 @default.
• W2009026789 hasConceptScore W2009026789C159654299 @default.
• W2009026789 hasConceptScore W2009026789C203014093 @default.
• W2009026789 hasConceptScore W2009026789C2777232031 @default.
• W2009026789 hasConceptScore W2009026789C2777702733 @default.
• W2009026789 hasConceptScore W2009026789C2778385053 @default.
• W2009026789 hasConceptScore W2009026789C2781413609 @default.
• W2009026789 hasConceptScore W2009026789C32611913 @default.
• W2009026789 hasConceptScore W2009026789C71924100 @default.
• W2009026789 hasConceptScore W2009026789C8891405 @default.
• W2009026789 hasConceptScore W2009026789C90924648 @default.
• W2009026789 hasIssue "2" @default.
• W2009026789 hasLocation W20090267891 @default.
• W2009026789 hasLocation W20090267892 @default.
• W2009026789 hasOpenAccess W2009026789 @default.
• W2009026789 hasPrimaryLocation W20090267891 @default.
• W2009026789 hasRelatedWork W1995822104 @default.
• W2009026789 hasRelatedWork W2005719195 @default.

• next