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- W2009042106 abstract "An efficient method for the solid-phase synthesis of N,N′-substituted acylguanidines is presented. The key-step involves the N-acylation of resin immobilized S-methylisothiourea with a variety of carboxylic acids using PyAOP as the coupling agent. The resulting resin bound N-acyl-derivatives are reacted with a host of amines and the N-acyl,N′-alkyl(aryl)guanidines liberated from the resin upon exposure to TFA." @default.
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- W2009042106 title "Solid-phase synthesis of N , N ′-substituted acylguanidines" @default.
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- W2009042106 doi "https://doi.org/10.1016/s0040-4039(00)02265-6" @default.
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