Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009042237> ?p ?o ?g. }
- W2009042237 endingPage "1291" @default.
- W2009042237 startingPage "1282" @default.
- W2009042237 abstract "In patients with cirrhosis, adrenal insufficiency (AI) is reported during sepsis and septic shock and is associated with increased mortality. Consequently, the term “hepato-adrenal syndrome” was proposed. Some studies have shown that AI is frequent in stable cirrhosis as well as in cirrhosis associated with decompensation other than sepsis, such as bleeding and ascites. Moreover, other studies showed a high prevalence in liver transplant recipients immediately after, or some time after, liver transplantation. The effect of corticosteroid therapy in critically ill patients with liver disease has been evaluated in some studies, but the results remain controversial. The 250-μg adreno-cortico-tropic-hormone stimulation test to diagnose AI in critically ill adult patients is recommended by an international task force. However, in liver disease, there is no consensus on the appropriate tests and normal values to assess adrenal function; thus, standardization of normal ranges and methodology is needed. Serum total cortisol assays overestimate AI in patients with cirrhosis, so that direct free cortisol measurement or its surrogates may be useful measurements to define AI, but further studies are needed to clarify this. In addition, the mechanisms by which liver disease leads to adrenal dysfunction are not sufficiently documented. This review evaluates published data regarding adrenal function in patients with liver disease, with a particular focus on the potential limitations of these studies as well as suggestions for future studies. (HEPATOLOGY 2012)" @default.
- W2009042237 created "2016-06-24" @default.
- W2009042237 creator A5009813811 @default.
- W2009042237 creator A5009873146 @default.
- W2009042237 creator A5020101597 @default.
- W2009042237 creator A5023354023 @default.
- W2009042237 creator A5044017759 @default.
- W2009042237 creator A5067638697 @default.
- W2009042237 creator A5073613780 @default.
- W2009042237 creator A5076412306 @default.
- W2009042237 creator A5079372889 @default.
- W2009042237 creator A5089559950 @default.
- W2009042237 date "2012-03-27" @default.
- W2009042237 modified "2023-09-27" @default.
- W2009042237 title "Adrenocortical dysfunction in liver disease: A systematic review" @default.
- W2009042237 cites W1804294633 @default.
- W2009042237 cites W1964995303 @default.
- W2009042237 cites W1966259559 @default.
- W2009042237 cites W1967265097 @default.
- W2009042237 cites W1997644403 @default.
- W2009042237 cites W2004014902 @default.
- W2009042237 cites W2005908626 @default.
- W2009042237 cites W2009160587 @default.
- W2009042237 cites W2018999941 @default.
- W2009042237 cites W2021823088 @default.
- W2009042237 cites W2033894089 @default.
- W2009042237 cites W2043539638 @default.
- W2009042237 cites W2054168229 @default.
- W2009042237 cites W2061918524 @default.
- W2009042237 cites W2068297810 @default.
- W2009042237 cites W2071276823 @default.
- W2009042237 cites W2071675531 @default.
- W2009042237 cites W2072002496 @default.
- W2009042237 cites W2072627503 @default.
- W2009042237 cites W2080245361 @default.
- W2009042237 cites W2080321582 @default.
- W2009042237 cites W2082235567 @default.
- W2009042237 cites W2084915114 @default.
- W2009042237 cites W2093715537 @default.
- W2009042237 cites W2094459400 @default.
- W2009042237 cites W2100045068 @default.
- W2009042237 cites W2110535212 @default.
- W2009042237 cites W2110686105 @default.
- W2009042237 cites W2116598229 @default.
- W2009042237 cites W2125017989 @default.
- W2009042237 cites W2126386774 @default.
- W2009042237 cites W2131752475 @default.
- W2009042237 cites W2138657423 @default.
- W2009042237 cites W2142868723 @default.
- W2009042237 cites W2142927411 @default.
- W2009042237 cites W2158930864 @default.
- W2009042237 cites W4249152248 @default.
- W2009042237 doi "https://doi.org/10.1002/hep.25573" @default.
- W2009042237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22234976" @default.
- W2009042237 hasPublicationYear "2012" @default.
- W2009042237 type Work @default.
- W2009042237 sameAs 2009042237 @default.
- W2009042237 citedByCount "106" @default.
- W2009042237 countsByYear W20090422372012 @default.
- W2009042237 countsByYear W20090422372013 @default.
- W2009042237 countsByYear W20090422372014 @default.
- W2009042237 countsByYear W20090422372015 @default.
- W2009042237 countsByYear W20090422372016 @default.
- W2009042237 countsByYear W20090422372017 @default.
- W2009042237 countsByYear W20090422372018 @default.
- W2009042237 countsByYear W20090422372019 @default.
- W2009042237 countsByYear W20090422372020 @default.
- W2009042237 countsByYear W20090422372021 @default.
- W2009042237 countsByYear W20090422372022 @default.
- W2009042237 countsByYear W20090422372023 @default.
- W2009042237 crossrefType "journal-article" @default.
- W2009042237 hasAuthorship W2009042237A5009813811 @default.
- W2009042237 hasAuthorship W2009042237A5009873146 @default.
- W2009042237 hasAuthorship W2009042237A5020101597 @default.
- W2009042237 hasAuthorship W2009042237A5023354023 @default.
- W2009042237 hasAuthorship W2009042237A5044017759 @default.
- W2009042237 hasAuthorship W2009042237A5067638697 @default.
- W2009042237 hasAuthorship W2009042237A5073613780 @default.
- W2009042237 hasAuthorship W2009042237A5076412306 @default.
- W2009042237 hasAuthorship W2009042237A5079372889 @default.
- W2009042237 hasAuthorship W2009042237A5089559950 @default.
- W2009042237 hasConcept C126322002 @default.
- W2009042237 hasConcept C177713679 @default.
- W2009042237 hasConcept C2777075537 @default.
- W2009042237 hasConcept C2777214474 @default.
- W2009042237 hasConcept C2777628635 @default.
- W2009042237 hasConcept C2778129406 @default.
- W2009042237 hasConcept C2778384902 @default.
- W2009042237 hasConcept C2778721985 @default.
- W2009042237 hasConcept C2779134260 @default.
- W2009042237 hasConcept C2779609443 @default.
- W2009042237 hasConcept C2780496750 @default.
- W2009042237 hasConcept C2911091166 @default.
- W2009042237 hasConcept C41260117 @default.
- W2009042237 hasConcept C512861765 @default.
- W2009042237 hasConcept C71924100 @default.
- W2009042237 hasConcept C90924648 @default.
- W2009042237 hasConceptScore W2009042237C126322002 @default.