Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009043598> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2009043598 endingPage "209" @default.
- W2009043598 startingPage "199" @default.
- W2009043598 abstract "The cell specific induction of uridine diphosphate(UDP)-glucuronyltransferase by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in intestinal epithelium was studied by administering [14C]TCDD (8 μg/kg to adult female rats). Intact epithelial cells from the tip and crypt regions were isolated by differential vibration of rat duodenum. Cell separation was monitored by electron microscopy and marker enzymes. UDP-glucuronyltransferase and radioactivity were assayed in both cell types 0 h, 3 h, 10 h, 1 day, 3 days and 5 days after treatment. UDP-glucuronyltransferase activities were not significantly changed in either cell type isolated from TCDD-treated rats until 24 hr after treatment when a three-fold increase in crypt cell activity was evident. No significant changes in UDP-glucuronyltransferase activity were observed in the differentiated tip cells until 3 days after TCDD treatment. UDP-glucuronyltransferase was increased approximately two-fold in both cell types from 3 and 5 days following TCDD treatment. There was a negative correlation between the time-course of UDP-glucuronyltransferase induction and the [14C]TCDD concentrations measured in these cells. These studies suggest that the undifferentiated cells of the intestinal crypt region are more sensitive to TCDD inductive actions than are the absorptive tip cells." @default.
- W2009043598 created "2016-06-24" @default.
- W2009043598 creator A5075789229 @default.
- W2009043598 creator A5087804604 @default.
- W2009043598 date "1978-09-01" @default.
- W2009043598 modified "2023-09-23" @default.
- W2009043598 title "The differential response of isolated intestinal crypt and tip cells to the inductive actions of 2,3,7,8-tetrachlorodibenzo-p-dioxin" @default.
- W2009043598 cites W1469613096 @default.
- W2009043598 cites W1577296862 @default.
- W2009043598 cites W1775749144 @default.
- W2009043598 cites W1970587768 @default.
- W2009043598 cites W1991992860 @default.
- W2009043598 cites W1995907069 @default.
- W2009043598 cites W2003741178 @default.
- W2009043598 cites W2014588512 @default.
- W2009043598 cites W2024814047 @default.
- W2009043598 cites W2032925961 @default.
- W2009043598 cites W2035038476 @default.
- W2009043598 cites W2060171140 @default.
- W2009043598 cites W2067669375 @default.
- W2009043598 cites W2076177517 @default.
- W2009043598 cites W2076539907 @default.
- W2009043598 cites W2080345024 @default.
- W2009043598 cites W2084142664 @default.
- W2009043598 doi "https://doi.org/10.1016/0009-2797(78)90125-4" @default.
- W2009043598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/100229" @default.
- W2009043598 hasPublicationYear "1978" @default.
- W2009043598 type Work @default.
- W2009043598 sameAs 2009043598 @default.
- W2009043598 citedByCount "18" @default.
- W2009043598 crossrefType "journal-article" @default.
- W2009043598 hasAuthorship W2009043598A5075789229 @default.
- W2009043598 hasAuthorship W2009043598A5087804604 @default.
- W2009043598 hasConcept C126322002 @default.
- W2009043598 hasConcept C134018914 @default.
- W2009043598 hasConcept C1491633281 @default.
- W2009043598 hasConcept C160160445 @default.
- W2009043598 hasConcept C181199279 @default.
- W2009043598 hasConcept C185592680 @default.
- W2009043598 hasConcept C189014844 @default.
- W2009043598 hasConcept C2778152042 @default.
- W2009043598 hasConcept C2909724048 @default.
- W2009043598 hasConcept C29730261 @default.
- W2009043598 hasConcept C55493867 @default.
- W2009043598 hasConcept C66090201 @default.
- W2009043598 hasConcept C71924100 @default.
- W2009043598 hasConcept C86803240 @default.
- W2009043598 hasConceptScore W2009043598C126322002 @default.
- W2009043598 hasConceptScore W2009043598C134018914 @default.
- W2009043598 hasConceptScore W2009043598C1491633281 @default.
- W2009043598 hasConceptScore W2009043598C160160445 @default.
- W2009043598 hasConceptScore W2009043598C181199279 @default.
- W2009043598 hasConceptScore W2009043598C185592680 @default.
- W2009043598 hasConceptScore W2009043598C189014844 @default.
- W2009043598 hasConceptScore W2009043598C2778152042 @default.
- W2009043598 hasConceptScore W2009043598C2909724048 @default.
- W2009043598 hasConceptScore W2009043598C29730261 @default.
- W2009043598 hasConceptScore W2009043598C55493867 @default.
- W2009043598 hasConceptScore W2009043598C66090201 @default.
- W2009043598 hasConceptScore W2009043598C71924100 @default.
- W2009043598 hasConceptScore W2009043598C86803240 @default.
- W2009043598 hasIssue "2-3" @default.
- W2009043598 hasLocation W20090435981 @default.
- W2009043598 hasLocation W20090435982 @default.
- W2009043598 hasOpenAccess W2009043598 @default.
- W2009043598 hasPrimaryLocation W20090435981 @default.
- W2009043598 hasRelatedWork W1994093574 @default.
- W2009043598 hasRelatedWork W2069809363 @default.
- W2009043598 hasRelatedWork W2074028842 @default.
- W2009043598 hasRelatedWork W2074405142 @default.
- W2009043598 hasRelatedWork W2075423832 @default.
- W2009043598 hasRelatedWork W2077608581 @default.
- W2009043598 hasRelatedWork W2149440651 @default.
- W2009043598 hasRelatedWork W2153389651 @default.
- W2009043598 hasRelatedWork W2397759342 @default.
- W2009043598 hasRelatedWork W4244070664 @default.
- W2009043598 hasVolume "22" @default.
- W2009043598 isParatext "false" @default.
- W2009043598 isRetracted "false" @default.
- W2009043598 magId "2009043598" @default.
- W2009043598 workType "article" @default.