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• W2009043962 abstract "ABSTRACT After penetrating the host cell, the herpesvirus capsid is transported to the nucleus along the microtubule network and docks to the nuclear pore complex before releasing the viral DNA into the nucleus. The viral and cellular interactions involved in the docking process are poorly characterized. However, the minor capsid protein pUL25 has recently been reported to be involved in viral DNA uncoating. Here we show that herpes simplex virus type 1 (HSV-1) capsids interact with the nucleoporin CAN/Nup214 in infected cells and that RNA silencing of CAN/Nup214 delays the onset of viral DNA replication in the nucleus. We also show that pUL25 interacts with CAN/Nup214 and another nucleoporin, hCG1, and binds to the pUL36 and pUL6 proteins, two other components of the herpesvirus particle that are known to be important for the initiation of infection and viral DNA release. These results identify CAN/Nup214 as being a nuclear receptor for the herpesvirus capsid and pUL25 as being an interface between incoming capsids and the nuclear pore complex and as being a triggering element for viral DNA release into the nucleus." @default.
• W2009043962 created "2016-06-24" @default.
• W2009043962 creator A5000509930 @default.
• W2009043962 creator A5001010613 @default.
• W2009043962 creator A5013902011 @default.
• W2009043962 creator A5091335960 @default.
• W2009043962 date "2009-07-01" @default.
• W2009043962 modified "2023-09-30" @default.
• W2009043962 title "Herpesvirus Capsid Association with the Nuclear Pore Complex and Viral DNA Release Involve the Nucleoporin CAN/Nup214 and the Capsid Protein pUL25" @default.
• W2009043962 cites W1519594915 @default.
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• W2009043962 cites W1591020212 @default.
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• W2009043962 cites W1820557301 @default.
• W2009043962 cites W1966729098 @default.
• W2009043962 cites W1968252416 @default.
• W2009043962 cites W1968605428 @default.
• W2009043962 cites W1968697793 @default.
• W2009043962 cites W1968975193 @default.
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• W2009043962 doi "https://doi.org/10.1128/jvi.02655-08" @default.
• W2009043962 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2698519" @default.
• W2009043962 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19386703" @default.
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