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- W2009077404 abstract "A reaction-motivated fluorescent probe for thiols was designed and synthesized containing binaphthalene fluorophore and maleimide binding group. The probe showed high selectivity and sensitivity for thiol-containing amino acids (Cys, Hcy, GSH) over other amino acids with detectable fluorescent signals in aqueous-DMSO media. The proposed mechanism is that the fluorescence of the probe was enhanced due to the thiol reacting with the CC double bond of the maleimide group, and blocking the ICT process from the binaphthalene moiety to the maleimide group, resulting in a recovery of the emission of the binaphthalene fluorophore, and the adduct was proved by ESI-MS and 1H NMR analysis. Furthermore, this probe successfully applied to bioimaging, demonstrating its value of practical applications in biological systems." @default.
- W2009077404 created "2016-06-24" @default.
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- W2009077404 date "2015-02-01" @default.
- W2009077404 modified "2023-10-16" @default.
- W2009077404 title "An off–on fluorescent probe based on maleimide for detecting thiols and its application for bioimaging" @default.
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- W2009077404 doi "https://doi.org/10.1016/j.snb.2014.09.091" @default.
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