FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009095268> ?p ?o ?g. }

• W2009095268 endingPage "617" @default.
• W2009095268 startingPage "611" @default.
• W2009095268 abstract "1,5-Anhydro-d-glucitol (1,5-AG) is fairly widespread in food products. It is also one of the major polyols in the human body, and its concentration is homeostatically regulated. We report here on the beneficial effects of 1,5-AG in preventing hyperglycemia and its role in improving metabolic syndrome. The findings revealed that it does not affect blood glucose levels itself under normal conditions but clearly has a suppressive effect on the levels of dietary sugars, such as glucose, maltose, and sucrose. A long-term administration study revealed that feeding db/db diabetic mice 3% 1,5-AG for 8 weeks significantly decreased blood glucose levels compared to untreated mice (339 ± 30 versus 438 ± 34 mg/dL; p < 0.05). Furthermore, this treatment also significantly suppressed serum cholesterol levels (110.2 ± 18.0 versus 168.4 ± 9.8 mg/dL; p < 0.01). 1,5-AG did not inhibit intestinal α-glucosidase activities but regulated liver glucose levels via affecting both the glycogenolysis and gluconeogenesis pathways. Furthermore, the oral administration of 1,5-AG significantly increased urinary glucose excretion in hyperglycemic conditions. These results clearly suggest that dietary 1,5-AG acts as a modulator of glucose levels in hyperglycemia. 1,5-AG therefore represents a new class of promising functional sweeteners, where the daily consumption of 1,5-AG with meals could inhibit the progress of hyperglycemia and metabolic syndrome." @default.
• W2009095268 created "2016-06-24" @default.
• W2009095268 creator A5006167254 @default.
• W2009095268 creator A5023986742 @default.
• W2009095268 creator A5076082941 @default.
• W2009095268 creator A5082223592 @default.
• W2009095268 creator A5087333213 @default.
• W2009095268 creator A5087412950 @default.
• W2009095268 date "2013-01-11" @default.
• W2009095268 modified "2023-10-03" @default.
• W2009095268 title "Protective Effects of Dietary 1,5-Anhydro-<scp>d</scp>-glucitol as a Blood Glucose Regulator in Diabetes and Metabolic Syndrome" @default.
• W2009095268 cites W1522314688 @default.
• W2009095268 cites W152894524 @default.
• W2009095268 cites W1561949950 @default.
• W2009095268 cites W186822690 @default.
• W2009095268 cites W1932740246 @default.
• W2009095268 cites W1966234811 @default.
• W2009095268 cites W1974115114 @default.
• W2009095268 cites W1981813882 @default.
• W2009095268 cites W1982261994 @default.
• W2009095268 cites W1992821910 @default.
• W2009095268 cites W1996337164 @default.
• W2009095268 cites W2000319168 @default.
• W2009095268 cites W2000643989 @default.
• W2009095268 cites W2011073664 @default.
• W2009095268 cites W2011942248 @default.
• W2009095268 cites W2018316592 @default.
• W2009095268 cites W2025645904 @default.
• W2009095268 cites W2029056840 @default.
• W2009095268 cites W2029749250 @default.
• W2009095268 cites W2038856804 @default.
• W2009095268 cites W2046302653 @default.
• W2009095268 cites W2051314001 @default.
• W2009095268 cites W2067519102 @default.
• W2009095268 cites W2070687687 @default.
• W2009095268 cites W2072598145 @default.
• W2009095268 cites W2096546427 @default.
• W2009095268 cites W2099042663 @default.
• W2009095268 cites W2101508556 @default.
• W2009095268 cites W2123946565 @default.
• W2009095268 cites W2146877877 @default.
• W2009095268 cites W2149185387 @default.
• W2009095268 cites W2166559722 @default.
• W2009095268 cites W2166672162 @default.
• W2009095268 cites W2168485217 @default.
• W2009095268 cites W2188846692 @default.
• W2009095268 cites W2328389184 @default.
• W2009095268 cites W2337454357 @default.
• W2009095268 doi "https://doi.org/10.1021/jf304683s" @default.
• W2009095268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23270454" @default.
• W2009095268 hasPublicationYear "2013" @default.
• W2009095268 type Work @default.
• W2009095268 sameAs 2009095268 @default.
• W2009095268 citedByCount "13" @default.
• W2009095268 countsByYear W20090952682014 @default.
• W2009095268 countsByYear W20090952682016 @default.
• W2009095268 countsByYear W20090952682017 @default.
• W2009095268 countsByYear W20090952682020 @default.
• W2009095268 countsByYear W20090952682022 @default.
• W2009095268 countsByYear W20090952682023 @default.
• W2009095268 crossrefType "journal-article" @default.
• W2009095268 hasAuthorship W2009095268A5006167254 @default.
• W2009095268 hasAuthorship W2009095268A5023986742 @default.
• W2009095268 hasAuthorship W2009095268A5076082941 @default.
• W2009095268 hasAuthorship W2009095268A5082223592 @default.
• W2009095268 hasAuthorship W2009095268A5087333213 @default.
• W2009095268 hasAuthorship W2009095268A5087412950 @default.
• W2009095268 hasConcept C126322002 @default.
• W2009095268 hasConcept C134018914 @default.
• W2009095268 hasConcept C185592680 @default.
• W2009095268 hasConcept C20904676 @default.
• W2009095268 hasConcept C2777949327 @default.
• W2009095268 hasConcept C2778197599 @default.
• W2009095268 hasConcept C2778597767 @default.
• W2009095268 hasConcept C55493867 @default.
• W2009095268 hasConcept C555293320 @default.
• W2009095268 hasConcept C62231903 @default.
• W2009095268 hasConcept C71924100 @default.
• W2009095268 hasConcept C76923068 @default.
• W2009095268 hasConcept C86803240 @default.
• W2009095268 hasConceptScore W2009095268C126322002 @default.
• W2009095268 hasConceptScore W2009095268C134018914 @default.
• W2009095268 hasConceptScore W2009095268C185592680 @default.
• W2009095268 hasConceptScore W2009095268C20904676 @default.
• W2009095268 hasConceptScore W2009095268C2777949327 @default.
• W2009095268 hasConceptScore W2009095268C2778197599 @default.
• W2009095268 hasConceptScore W2009095268C2778597767 @default.
• W2009095268 hasConceptScore W2009095268C55493867 @default.
• W2009095268 hasConceptScore W2009095268C555293320 @default.
• W2009095268 hasConceptScore W2009095268C62231903 @default.
• W2009095268 hasConceptScore W2009095268C71924100 @default.
• W2009095268 hasConceptScore W2009095268C76923068 @default.
• W2009095268 hasConceptScore W2009095268C86803240 @default.
• W2009095268 hasIssue "3" @default.
• W2009095268 hasLocation W20090952681 @default.
• W2009095268 hasLocation W20090952682 @default.
• W2009095268 hasOpenAccess W2009095268 @default.
• W2009095268 hasPrimaryLocation W20090952681 @default.

• next