Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009103652> ?p ?o ?g. }
- W2009103652 endingPage "1693" @default.
- W2009103652 startingPage "1685" @default.
- W2009103652 abstract "Abstract The ability of extracellular stimuli to modulate dendritic cell (DC) activation of natural killer T (NKT) cells was not well understood. We investigated the effects of the T helper type 1 (Th1)/Th2-cytokine environment on DC induction of NKT cell-mediated cytokine production in mice. Pretreatment of myeloid DCs with Th1 or Th2 cytokines, interleukin (IL)-4 or interferon (IFN)-γ, led to the enhanced production of reciprocal cytokines by NKT cells (eg, IL-4 pretreatment led to the enhanced production of Th1 cytokines) in vitro and in vivo. Thus, the recognition of Th1 or Th2 cytokines by DCs acts as a negative feedback loop to maintain Th1/Th2-cytokine balance via NKT cell functions. Using these data, we manipulated cytokine levels and innate cytolytic activity in vivo to increase an antitumor response. This is the first description of a novel regulation system governing Th1/Th2 cytokine balance involving DCs and NKT cells. (Blood. 2005;106:1685-1693)" @default.
- W2009103652 created "2016-06-24" @default.
- W2009103652 creator A5002093001 @default.
- W2009103652 creator A5005875682 @default.
- W2009103652 creator A5010806066 @default.
- W2009103652 creator A5047099961 @default.
- W2009103652 creator A5056802168 @default.
- W2009103652 creator A5064546023 @default.
- W2009103652 creator A5067926596 @default.
- W2009103652 date "2005-09-01" @default.
- W2009103652 modified "2023-10-18" @default.
- W2009103652 title "Negative feedback regulation of T helper type 1 (Th1)/Th2 cytokine balance via dendritic cell and natural killer T cell interactions" @default.
- W2009103652 cites W1515882146 @default.
- W2009103652 cites W1517017118 @default.
- W2009103652 cites W1566974294 @default.
- W2009103652 cites W1568945049 @default.
- W2009103652 cites W1648566400 @default.
- W2009103652 cites W1661544713 @default.
- W2009103652 cites W1828221682 @default.
- W2009103652 cites W1900981725 @default.
- W2009103652 cites W1970548110 @default.
- W2009103652 cites W1976690411 @default.
- W2009103652 cites W1979711271 @default.
- W2009103652 cites W1981649463 @default.
- W2009103652 cites W2024351056 @default.
- W2009103652 cites W2024754275 @default.
- W2009103652 cites W2024843941 @default.
- W2009103652 cites W2048724356 @default.
- W2009103652 cites W2059313909 @default.
- W2009103652 cites W2062373696 @default.
- W2009103652 cites W2063871374 @default.
- W2009103652 cites W2065792487 @default.
- W2009103652 cites W2071652403 @default.
- W2009103652 cites W2097438831 @default.
- W2009103652 cites W2098942224 @default.
- W2009103652 cites W2101080683 @default.
- W2009103652 cites W2101642059 @default.
- W2009103652 cites W2104595633 @default.
- W2009103652 cites W2104910525 @default.
- W2009103652 cites W2112643590 @default.
- W2009103652 cites W2116716017 @default.
- W2009103652 cites W2120943145 @default.
- W2009103652 cites W2125401864 @default.
- W2009103652 cites W2127136381 @default.
- W2009103652 cites W2135904518 @default.
- W2009103652 cites W2140179235 @default.
- W2009103652 cites W2144821901 @default.
- W2009103652 cites W2146463760 @default.
- W2009103652 cites W2148115090 @default.
- W2009103652 cites W2157278565 @default.
- W2009103652 cites W2161307276 @default.
- W2009103652 cites W2165658685 @default.
- W2009103652 cites W2170266529 @default.
- W2009103652 cites W2177327503 @default.
- W2009103652 cites W4230688060 @default.
- W2009103652 cites W4313146958 @default.
- W2009103652 cites W4313335791 @default.
- W2009103652 cites W4313335817 @default.
- W2009103652 cites W4321429285 @default.
- W2009103652 cites W90568390 @default.
- W2009103652 doi "https://doi.org/10.1182/blood-2004-12-4738" @default.
- W2009103652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15878981" @default.
- W2009103652 hasPublicationYear "2005" @default.
- W2009103652 type Work @default.
- W2009103652 sameAs 2009103652 @default.
- W2009103652 citedByCount "32" @default.
- W2009103652 countsByYear W20091036522012 @default.
- W2009103652 countsByYear W20091036522013 @default.
- W2009103652 countsByYear W20091036522014 @default.
- W2009103652 countsByYear W20091036522016 @default.
- W2009103652 countsByYear W20091036522019 @default.
- W2009103652 countsByYear W20091036522023 @default.
- W2009103652 crossrefType "journal-article" @default.
- W2009103652 hasAuthorship W2009103652A5002093001 @default.
- W2009103652 hasAuthorship W2009103652A5005875682 @default.
- W2009103652 hasAuthorship W2009103652A5010806066 @default.
- W2009103652 hasAuthorship W2009103652A5047099961 @default.
- W2009103652 hasAuthorship W2009103652A5056802168 @default.
- W2009103652 hasAuthorship W2009103652A5064546023 @default.
- W2009103652 hasAuthorship W2009103652A5067926596 @default.
- W2009103652 hasBestOaLocation W20091036521 @default.
- W2009103652 hasConcept C139563560 @default.
- W2009103652 hasConcept C202751555 @default.
- W2009103652 hasConcept C203014093 @default.
- W2009103652 hasConcept C26291073 @default.
- W2009103652 hasConcept C2776090121 @default.
- W2009103652 hasConcept C2778170410 @default.
- W2009103652 hasConcept C2778690821 @default.
- W2009103652 hasConcept C2781136212 @default.
- W2009103652 hasConcept C55493867 @default.
- W2009103652 hasConcept C86803240 @default.
- W2009103652 hasConcept C8891405 @default.
- W2009103652 hasConcept C95444343 @default.
- W2009103652 hasConceptScore W2009103652C139563560 @default.
- W2009103652 hasConceptScore W2009103652C202751555 @default.
- W2009103652 hasConceptScore W2009103652C203014093 @default.
- W2009103652 hasConceptScore W2009103652C26291073 @default.
- W2009103652 hasConceptScore W2009103652C2776090121 @default.