Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009188525> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2009188525 endingPage "F8" @default.
- W2009188525 startingPage "F6" @default.
- W2009188525 abstract "Calcium fluxes play a key role in controlling many physiologic processes and responses in the body. The past few years have witnessed major advances in understanding of L-type calcium channels and their blockade with calcium channel antagonists. The L-type calcium channels comprise 5 subunits termed α1, α2, β, γ, and δ. Elucidation of the mechanisms of action of the calcium channel antagonists has been advanced by cloning and genetic manipulation of these subunits. The α1 subunit appears to be responsible for channel opening and voltage dependency, and it contains receptors for calcium channel antagonists; these geographically distinct receptors correspond to each of the 3 different chemical classes of antagonists, exemplified by diltiazem, nlfedlpine, and verapamil. Diltiazem appears to have an inhibitory effect on mitochondrial sodium-calcium exchange that is unique among calcium channel antagonists. Preliminary data suggest that a diltiazem-specific receptor also exists in the endothelium. It appears, therefore, that despite advances in the understanding of L-type calcium channels, much remains to be learned about other possible receptors for the calcium channel antagonists." @default.
- W2009188525 created "2016-06-24" @default.
- W2009188525 creator A5073170005 @default.
- W2009188525 date "1992-11-01" @default.
- W2009188525 modified "2023-09-27" @default.
- W2009188525 title "Molecular and cellular aspects of calcium channel antagonism" @default.
- W2009188525 cites W1627770206 @default.
- W2009188525 cites W1998318605 @default.
- W2009188525 cites W2006192148 @default.
- W2009188525 cites W2022186297 @default.
- W2009188525 cites W2027156597 @default.
- W2009188525 cites W2046668603 @default.
- W2009188525 cites W2087651417 @default.
- W2009188525 cites W2117405745 @default.
- W2009188525 cites W2322661993 @default.
- W2009188525 doi "https://doi.org/10.1016/0002-9149(92)90182-x" @default.
- W2009188525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1332464" @default.
- W2009188525 hasPublicationYear "1992" @default.
- W2009188525 type Work @default.
- W2009188525 sameAs 2009188525 @default.
- W2009188525 citedByCount "30" @default.
- W2009188525 countsByYear W20091885252013 @default.
- W2009188525 countsByYear W20091885252014 @default.
- W2009188525 countsByYear W20091885252016 @default.
- W2009188525 crossrefType "journal-article" @default.
- W2009188525 hasAuthorship W2009188525A5073170005 @default.
- W2009188525 hasConcept C117499352 @default.
- W2009188525 hasConcept C126322002 @default.
- W2009188525 hasConcept C134018914 @default.
- W2009188525 hasConcept C166832727 @default.
- W2009188525 hasConcept C170493617 @default.
- W2009188525 hasConcept C174293024 @default.
- W2009188525 hasConcept C18699975 @default.
- W2009188525 hasConcept C2776741139 @default.
- W2009188525 hasConcept C2777022698 @default.
- W2009188525 hasConcept C2780356492 @default.
- W2009188525 hasConcept C30979828 @default.
- W2009188525 hasConcept C519063684 @default.
- W2009188525 hasConcept C71924100 @default.
- W2009188525 hasConcept C85520022 @default.
- W2009188525 hasConcept C86803240 @default.
- W2009188525 hasConcept C92645518 @default.
- W2009188525 hasConcept C98274493 @default.
- W2009188525 hasConceptScore W2009188525C117499352 @default.
- W2009188525 hasConceptScore W2009188525C126322002 @default.
- W2009188525 hasConceptScore W2009188525C134018914 @default.
- W2009188525 hasConceptScore W2009188525C166832727 @default.
- W2009188525 hasConceptScore W2009188525C170493617 @default.
- W2009188525 hasConceptScore W2009188525C174293024 @default.
- W2009188525 hasConceptScore W2009188525C18699975 @default.
- W2009188525 hasConceptScore W2009188525C2776741139 @default.
- W2009188525 hasConceptScore W2009188525C2777022698 @default.
- W2009188525 hasConceptScore W2009188525C2780356492 @default.
- W2009188525 hasConceptScore W2009188525C30979828 @default.
- W2009188525 hasConceptScore W2009188525C519063684 @default.
- W2009188525 hasConceptScore W2009188525C71924100 @default.
- W2009188525 hasConceptScore W2009188525C85520022 @default.
- W2009188525 hasConceptScore W2009188525C86803240 @default.
- W2009188525 hasConceptScore W2009188525C92645518 @default.
- W2009188525 hasConceptScore W2009188525C98274493 @default.
- W2009188525 hasIssue "16" @default.
- W2009188525 hasLocation W20091885251 @default.
- W2009188525 hasLocation W20091885252 @default.
- W2009188525 hasOpenAccess W2009188525 @default.
- W2009188525 hasPrimaryLocation W20091885251 @default.
- W2009188525 hasRelatedWork W1994005583 @default.
- W2009188525 hasRelatedWork W2009188525 @default.
- W2009188525 hasRelatedWork W2031844916 @default.
- W2009188525 hasRelatedWork W2047213097 @default.
- W2009188525 hasRelatedWork W2050956561 @default.
- W2009188525 hasRelatedWork W2058619297 @default.
- W2009188525 hasRelatedWork W2915304397 @default.
- W2009188525 hasRelatedWork W3004827299 @default.
- W2009188525 hasRelatedWork W324768898 @default.
- W2009188525 hasRelatedWork W994978426 @default.
- W2009188525 hasVolume "70" @default.
- W2009188525 isParatext "false" @default.
- W2009188525 isRetracted "false" @default.
- W2009188525 magId "2009188525" @default.
- W2009188525 workType "article" @default.