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- W2009215664 abstract "Abstract: Controversy concerning the use of prophylactic antibiotics in breast surgery may be due to uncontrolled variability in infection risk among breast procedures, in surgical techniques used by different surgeons, or in length of follow-up at different institutions. In order to control variability, risk factors for postoperative infections after one breast procedure performed by a single surgeon with prolonged follow-up were evaluated. We studied 302 consecutive patients undergoing lumpectomy and axillary dissection by a single surgeon and followed for at least 6 months. Age, height, weight, Quetelet's index, diabetes, prophylactic antibiotics, re-excision of the biopsy site, tumor size, number of involved nodes and overall pathologic stage were evaluated using univariate and multivariate analysis. Eight patients (2.5%) developed wound infections within 30 days of surgery and an additional six (2%) developed infections between 30 days and 1 year. One (2.5%) of 41 patients who received prophylactic antibiotics developed an infection compared to 13 (5.2%) of the 261 patients who did not receive prophylactic antibiotics (chi-square = 0.103, p = 0.749). Eight (8%) of 103 patients diagnosed by ex-cisional biopsy prior to definitive surgery with re-excision of the biopsy site developed infections compared to 6 (3%) of the 199 patients who underwent surgery without re-excision (chi-square = 2.475, p = 0.116). There were also no statistically significant differences between patients with and without infections in age, height, weight, Quetelet's index, diabetes, tumor size, number of involved nodes, or overall pathologic stage. This data does not justify the use of prophylactic antibiotics for lumpectomy and axillary dissection." @default.
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- W2009215664 date "1997-03-01" @default.
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- W2009215664 title "The Significance of Risk Factors for Infection in Patients Undergoing Lumpectomy and Axillary Dissection" @default.
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- W2009215664 doi "https://doi.org/10.1111/j.1524-4741.1997.tb00146.x" @default.
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