FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009228936> ?p ?o ?g. }

• W2009228936 endingPage "10368" @default.
• W2009228936 startingPage "10368" @default.
• W2009228936 abstract "More than 50% of the world population is infected with Helicobacter pylori (H. pylori). The bacterium highly links to peptic ulcer diseases and duodenal ulcer, which was classified as a group I carcinogen in 1994 by the WHO. The pathogenesis of H. pylori is contributed by its virulence factors including urease, flagella, vacuolating cytotoxin A (VacA), cytotoxin-associated gene antigen (Cag A), and others. Of those virulence factors, VacA and CagA play the key roles. Infection with H. pylori vacA-positive strains can lead to vacuolation and apoptosis, whereas infection with cagA-positive strains might result in severe gastric inflammation and gastric cancer. Numerous medicinal plants have been reported for their anti-H. pylori activity, and the relevant active compounds including polyphenols, flavonoids, quinones, coumarins, terpenoids, and alkaloids have been studied. The anti-H. pylori action mechanisms, including inhibition of enzymatic (urease, DNA gyrase, dihydrofolate reductase, N-acetyltransferase, and myeloperoxidase) and adhesive activities, high redox potential, and hydrophilic/hydrophobic natures of compounds, have also been discussed in detail. H. pylori-induced gastric inflammation may progress to superficial gastritis, atrophic gastritis, and finally gastric cancer. Many natural products have anti-H. pylori-induced inflammation activity and the relevant mechanisms include suppression of nuclear factor-κB and mitogen-activated protein kinase pathway activation and inhibition of oxidative stress. Anti-H. pylori induced gastric inflammatory effects of plant products, including quercetin, apigenin, carotenoids-rich algae, tea product, garlic extract, apple peel polyphenol, and finger-root extract, have been documented. In conclusion, many medicinal plant products possess anti-H. pylori activity as well as an anti-H. pylori-induced gastric inflammatory effect. Those plant products have showed great potential as pharmaceutical candidates for H. pylori eradication and H. pylori induced related gastric disease prevention." @default.
• W2009228936 created "2016-06-24" @default.
• W2009228936 creator A5070898419 @default.
• W2009228936 date "2014-01-01" @default.
• W2009228936 modified "2023-10-11" @default.
• W2009228936 title "Medicinal plant activity on<i>Helicobacter pylori</i>related diseases" @default.
• W2009228936 cites W1500163247 @default.
• W2009228936 cites W1539606768 @default.
• W2009228936 cites W1909135811 @default.
• W2009228936 cites W1964343361 @default.
• W2009228936 cites W1964797140 @default.
• W2009228936 cites W1967381753 @default.
• W2009228936 cites W1969901996 @default.
• W2009228936 cites W1973236424 @default.
• W2009228936 cites W1973951560 @default.
• W2009228936 cites W1975527857 @default.
• W2009228936 cites W1975549382 @default.
• W2009228936 cites W1975600959 @default.
• W2009228936 cites W1975703577 @default.
• W2009228936 cites W1978396476 @default.
• W2009228936 cites W1978467942 @default.
• W2009228936 cites W1978588509 @default.
• W2009228936 cites W1978973147 @default.
• W2009228936 cites W1979798333 @default.
• W2009228936 cites W1981539096 @default.
• W2009228936 cites W1984695403 @default.
• W2009228936 cites W1986881589 @default.
• W2009228936 cites W1987572687 @default.
• W2009228936 cites W1989517400 @default.
• W2009228936 cites W1990010926 @default.
• W2009228936 cites W1990674888 @default.
• W2009228936 cites W1995804072 @default.
• W2009228936 cites W1997500389 @default.
• W2009228936 cites W1998630067 @default.
• W2009228936 cites W2001751680 @default.
• W2009228936 cites W2002577722 @default.
• W2009228936 cites W2005098963 @default.
• W2009228936 cites W2007731336 @default.
• W2009228936 cites W2007766909 @default.
• W2009228936 cites W2008949686 @default.
• W2009228936 cites W2010962258 @default.
• W2009228936 cites W2011483225 @default.
• W2009228936 cites W2015233091 @default.
• W2009228936 cites W2016927265 @default.
• W2009228936 cites W2023654730 @default.
• W2009228936 cites W2023911001 @default.
• W2009228936 cites W2024379827 @default.
• W2009228936 cites W2026063842 @default.
• W2009228936 cites W2027305673 @default.
• W2009228936 cites W2028823822 @default.
• W2009228936 cites W2028986035 @default.
• W2009228936 cites W2033323055 @default.
• W2009228936 cites W2033697781 @default.
• W2009228936 cites W2037737090 @default.
• W2009228936 cites W2039782464 @default.
• W2009228936 cites W2047477624 @default.
• W2009228936 cites W2047909565 @default.
• W2009228936 cites W2049748793 @default.
• W2009228936 cites W2050143126 @default.
• W2009228936 cites W2050474036 @default.
• W2009228936 cites W2052881735 @default.
• W2009228936 cites W2054365280 @default.
• W2009228936 cites W2055243636 @default.
• W2009228936 cites W2059574805 @default.
• W2009228936 cites W2059781799 @default.
• W2009228936 cites W2060164476 @default.
• W2009228936 cites W2060512903 @default.
• W2009228936 cites W2061741506 @default.
• W2009228936 cites W2061910352 @default.
• W2009228936 cites W2065725233 @default.
• W2009228936 cites W2068069377 @default.
• W2009228936 cites W2070424942 @default.
• W2009228936 cites W2071583382 @default.
• W2009228936 cites W2071893133 @default.
• W2009228936 cites W2072469979 @default.
• W2009228936 cites W2074150439 @default.
• W2009228936 cites W2074295950 @default.
• W2009228936 cites W2077767418 @default.
• W2009228936 cites W2078657936 @default.
• W2009228936 cites W2080610608 @default.
• W2009228936 cites W2081831784 @default.
• W2009228936 cites W2081906965 @default.
• W2009228936 cites W2081921751 @default.
• W2009228936 cites W2081943983 @default.
• W2009228936 cites W2082888592 @default.
• W2009228936 cites W2085250408 @default.
• W2009228936 cites W2086988002 @default.
• W2009228936 cites W2092417926 @default.
• W2009228936 cites W2092569336 @default.
• W2009228936 cites W2094544968 @default.
• W2009228936 cites W2102619095 @default.
• W2009228936 cites W2103426933 @default.
• W2009228936 cites W2104276052 @default.
• W2009228936 cites W2110146639 @default.
• W2009228936 cites W2110346592 @default.
• W2009228936 cites W2110837175 @default.
• W2009228936 cites W2111603268 @default.
• W2009228936 cites W2113562905 @default.

• next