FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009244559> ?p ?o ?g. }

• W2009244559 endingPage "866" @default.
• W2009244559 startingPage "860" @default.
• W2009244559 abstract "Although recent neuroimaging studies have shown that painful stimuli can produce activity in multiple cortical areas, the question remains as to the role of each area in particular aspects of human pain perception. To solve this problem we used transcranial magnetic stimulation (TMS) as an 'interference approach' tool to test the consequence on pain perception of disrupting activity in several areas of cortex known to be activated by painful input.Weak CO(2) laser stimuli at an intensity around the threshold for pain were given to the dorsum of the left hand in 9 normal subjects. At variable delays (50, 150, 250, 350 ms) after the onset of the laser stimulus, pairs of TMS pulses (dTMS: interpulse interval of 50 ms, and stimulus intensity of 120% resting motor threshold) were applied in separate blocks of trials over either the right sensorimotor cortex (SMI), midline occipital cortex (OCC), second somatosensory cortex (SII), or medial frontal cortex (MFC). Subjects were instructed to judge whether or not the stimulus was painful and to point to the stimulated spot on a drawing of subject's hand.Subjects judged that the stimulus was painful on more trials than control when dTMS was delivered over SMI at 150-200 ms after the laser stimulus; the opposite occurred when dTMS was delivered over MFC at 50-100 ms. dTMS over the SII or OCC failed to alter the pain threshold.These results suggest that TMS to SMI can facilitate whereas stimulation over MFC suppresses central processing of pain perception. Since there was no effect of dTMS at any of the scalp sites on the localization task, the cortical locus for point localization of pain may be different from that for perception of pain intensity or may involve a more complex mechanism than the latter.This is the first report that TMS of SMI facilitates while that of MFC suppresses the central processing of pain perception. This raises the possibility of using TMS as a therapeutic device to control pain." @default.
• W2009244559 created "2016-06-24" @default.
• W2009244559 creator A5005183793 @default.
• W2009244559 creator A5007921825 @default.
• W2009244559 creator A5008515519 @default.
• W2009244559 creator A5013920139 @default.
• W2009244559 creator A5034555728 @default.
• W2009244559 creator A5037355919 @default.
• W2009244559 creator A5062706849 @default.
• W2009244559 creator A5068010875 @default.
• W2009244559 creator A5080477624 @default.
• W2009244559 creator A5088964079 @default.
• W2009244559 date "2003-05-01" @default.
• W2009244559 modified "2023-10-10" @default.
• W2009244559 title "Transcranial magnetic stimulation (TMS) of the sensorimotor cortex and medial frontal cortex modifies human pain perception" @default.
• W2009244559 cites W1694363227 @default.
• W2009244559 cites W1784320901 @default.
• W2009244559 cites W1801800938 @default.
• W2009244559 cites W1942645015 @default.
• W2009244559 cites W1963019205 @default.
• W2009244559 cites W1968280685 @default.
• W2009244559 cites W1969876540 @default.
• W2009244559 cites W1982865683 @default.
• W2009244559 cites W1983006199 @default.
• W2009244559 cites W1988701101 @default.
• W2009244559 cites W1993144487 @default.
• W2009244559 cites W1995450474 @default.
• W2009244559 cites W2012173710 @default.
• W2009244559 cites W2012802401 @default.
• W2009244559 cites W2014493574 @default.
• W2009244559 cites W2014953925 @default.
• W2009244559 cites W2025577666 @default.
• W2009244559 cites W2035469860 @default.
• W2009244559 cites W2045812316 @default.
• W2009244559 cites W2055279600 @default.
• W2009244559 cites W2057648909 @default.
• W2009244559 cites W2059017974 @default.
• W2009244559 cites W2061567159 @default.
• W2009244559 cites W2066608675 @default.
• W2009244559 cites W2082214113 @default.
• W2009244559 cites W2085955270 @default.
• W2009244559 cites W2090202944 @default.
• W2009244559 cites W2104135024 @default.
• W2009244559 cites W2128059165 @default.
• W2009244559 cites W2129291496 @default.
• W2009244559 cites W2133659981 @default.
• W2009244559 cites W2140047713 @default.
• W2009244559 cites W2143919010 @default.
• W2009244559 cites W2145949697 @default.
• W2009244559 cites W2148782689 @default.
• W2009244559 cites W2153021745 @default.
• W2009244559 cites W2161974313 @default.
• W2009244559 cites W2174853638 @default.
• W2009244559 cites W2189924253 @default.
• W2009244559 cites W2304644128 @default.
• W2009244559 cites W2308925199 @default.
• W2009244559 cites W2338351501 @default.
• W2009244559 cites W2418344023 @default.
• W2009244559 cites W4243796190 @default.
• W2009244559 cites W4376102781 @default.
• W2009244559 cites W58894278 @default.
• W2009244559 cites W87578060 @default.
• W2009244559 doi "https://doi.org/10.1016/s1388-2457(03)00034-8" @default.
• W2009244559 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12738431" @default.
• W2009244559 hasPublicationYear "2003" @default.
• W2009244559 type Work @default.
• W2009244559 sameAs 2009244559 @default.
• W2009244559 citedByCount "85" @default.
• W2009244559 countsByYear W20092445592012 @default.
• W2009244559 countsByYear W20092445592013 @default.
• W2009244559 countsByYear W20092445592014 @default.
• W2009244559 countsByYear W20092445592015 @default.
• W2009244559 countsByYear W20092445592016 @default.
• W2009244559 countsByYear W20092445592018 @default.
• W2009244559 countsByYear W20092445592019 @default.
• W2009244559 countsByYear W20092445592020 @default.
• W2009244559 countsByYear W20092445592021 @default.
• W2009244559 countsByYear W20092445592023 @default.
• W2009244559 crossrefType "journal-article" @default.
• W2009244559 hasAuthorship W2009244559A5005183793 @default.
• W2009244559 hasAuthorship W2009244559A5007921825 @default.
• W2009244559 hasAuthorship W2009244559A5008515519 @default.
• W2009244559 hasAuthorship W2009244559A5013920139 @default.
• W2009244559 hasAuthorship W2009244559A5034555728 @default.
• W2009244559 hasAuthorship W2009244559A5037355919 @default.
• W2009244559 hasAuthorship W2009244559A5062706849 @default.
• W2009244559 hasAuthorship W2009244559A5068010875 @default.
• W2009244559 hasAuthorship W2009244559A5080477624 @default.
• W2009244559 hasAuthorship W2009244559A5088964079 @default.
• W2009244559 hasConcept C15744967 @default.
• W2009244559 hasConcept C169760540 @default.
• W2009244559 hasConcept C172497186 @default.
• W2009244559 hasConcept C180747234 @default.
• W2009244559 hasConcept C24998067 @default.
• W2009244559 hasConcept C26760741 @default.
• W2009244559 hasConcept C2778373776 @default.
• W2009244559 hasConcept C2778581513 @default.
• W2009244559 hasConcept C2778586271 @default.

• next