FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009255619> ?p ?o ?g. }

• W2009255619 endingPage "2828" @default.
• W2009255619 startingPage "2824" @default.
• W2009255619 abstract "Resectable non-small-cell lung cancer (NSCLC) patients have poor prognosis, with 30–50% relapsing within 5 years. Current staging criteria do not fully capture the complexity of this disease. Survival could be improved by identification of those early-stage patients who are most likely to benefit from adjuvant therapy. Molecular classification by using mRNA expression profiles has led to multiple, poorly overlapping signatures. We hypothesized that differing statistical methodologies contribute to this lack of overlap. To test this hypothesis, we analyzed our previously published quantitative RT-PCR dataset with a semisupervised method. A 6-gene signature was identified and validated in 4 independent public microarray datasets that represent a range of tumor histologies and stages. This result demonstrated that at least 2 prognostic signatures can be derived from this single dataset. We next estimated the total number of prognostic signatures in this dataset with a 10-million-signature permutation study. Our 6-gene signature was among the top 0.02% of signatures with maximum verifiability, reaffirming its efficacy. Importantly, this analysis identified 1,789 unique signatures, implying that our dataset contains >500,000 verifiable prognostic signatures for NSCLC. This result appears to rationalize the observed lack of overlap among reported NSCLC prognostic signatures." @default.
• W2009255619 created "2016-06-24" @default.
• W2009255619 creator A5007657275 @default.
• W2009255619 creator A5016959101 @default.
• W2009255619 creator A5017288311 @default.
• W2009255619 creator A5023531951 @default.
• W2009255619 creator A5031467567 @default.
• W2009255619 creator A5055656807 @default.
• W2009255619 creator A5067008822 @default.
• W2009255619 creator A5073362806 @default.
• W2009255619 creator A5075347427 @default.
• W2009255619 date "2009-02-24" @default.
• W2009255619 modified "2023-10-16" @default.
• W2009255619 title "Prognostic gene signatures for non-small-cell lung cancer" @default.
• W2009255619 cites W1974350437 @default.
• W2009255619 cites W1993312546 @default.
• W2009255619 cites W1995719676 @default.
• W2009255619 cites W2000771269 @default.
• W2009255619 cites W2040218462 @default.
• W2009255619 cites W2043235003 @default.
• W2009255619 cites W2058451329 @default.
• W2009255619 cites W2075549113 @default.
• W2009255619 cites W2084001490 @default.
• W2009255619 cites W2097413644 @default.
• W2009255619 cites W2097554668 @default.
• W2009255619 cites W2097880716 @default.
• W2009255619 cites W2100625712 @default.
• W2009255619 cites W2121277505 @default.
• W2009255619 cites W2127342594 @default.
• W2009255619 cites W2128021317 @default.
• W2009255619 cites W2128985829 @default.
• W2009255619 cites W2129777204 @default.
• W2009255619 cites W2131438131 @default.
• W2009255619 cites W2141157880 @default.
• W2009255619 cites W2142351815 @default.
• W2009255619 cites W2150688669 @default.
• W2009255619 cites W2151725006 @default.
• W2009255619 cites W2158234609 @default.
• W2009255619 cites W2160450758 @default.
• W2009255619 cites W2164131844 @default.
• W2009255619 cites W4239714259 @default.
• W2009255619 doi "https://doi.org/10.1073/pnas.0809444106" @default.
• W2009255619 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2636731" @default.
• W2009255619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19196983" @default.
• W2009255619 hasPublicationYear "2009" @default.
• W2009255619 type Work @default.
• W2009255619 sameAs 2009255619 @default.
• W2009255619 citedByCount "186" @default.
• W2009255619 countsByYear W20092556192012 @default.
• W2009255619 countsByYear W20092556192013 @default.
• W2009255619 countsByYear W20092556192014 @default.
• W2009255619 countsByYear W20092556192015 @default.
• W2009255619 countsByYear W20092556192016 @default.
• W2009255619 countsByYear W20092556192017 @default.
• W2009255619 countsByYear W20092556192018 @default.
• W2009255619 countsByYear W20092556192019 @default.
• W2009255619 countsByYear W20092556192020 @default.
• W2009255619 countsByYear W20092556192021 @default.
• W2009255619 countsByYear W20092556192022 @default.
• W2009255619 countsByYear W20092556192023 @default.
• W2009255619 crossrefType "journal-article" @default.
• W2009255619 hasAuthorship W2009255619A5007657275 @default.
• W2009255619 hasAuthorship W2009255619A5016959101 @default.
• W2009255619 hasAuthorship W2009255619A5017288311 @default.
• W2009255619 hasAuthorship W2009255619A5023531951 @default.
• W2009255619 hasAuthorship W2009255619A5031467567 @default.
• W2009255619 hasAuthorship W2009255619A5055656807 @default.
• W2009255619 hasAuthorship W2009255619A5067008822 @default.
• W2009255619 hasAuthorship W2009255619A5073362806 @default.
• W2009255619 hasAuthorship W2009255619A5075347427 @default.
• W2009255619 hasBestOaLocation W20092556192 @default.
• W2009255619 hasConcept C104317684 @default.
• W2009255619 hasConcept C126322002 @default.
• W2009255619 hasConcept C143998085 @default.
• W2009255619 hasConcept C146357865 @default.
• W2009255619 hasConcept C150194340 @default.
• W2009255619 hasConcept C151730666 @default.
• W2009255619 hasConcept C18431079 @default.
• W2009255619 hasConcept C186836561 @default.
• W2009255619 hasConcept C2776256026 @default.
• W2009255619 hasConcept C2779733811 @default.
• W2009255619 hasConcept C54355233 @default.
• W2009255619 hasConcept C60644358 @default.
• W2009255619 hasConcept C70721500 @default.
• W2009255619 hasConcept C71924100 @default.
• W2009255619 hasConcept C8415881 @default.
• W2009255619 hasConcept C86803240 @default.
• W2009255619 hasConceptScore W2009255619C104317684 @default.
• W2009255619 hasConceptScore W2009255619C126322002 @default.
• W2009255619 hasConceptScore W2009255619C143998085 @default.
• W2009255619 hasConceptScore W2009255619C146357865 @default.
• W2009255619 hasConceptScore W2009255619C150194340 @default.
• W2009255619 hasConceptScore W2009255619C151730666 @default.
• W2009255619 hasConceptScore W2009255619C18431079 @default.
• W2009255619 hasConceptScore W2009255619C186836561 @default.
• W2009255619 hasConceptScore W2009255619C2776256026 @default.
• W2009255619 hasConceptScore W2009255619C2779733811 @default.
• W2009255619 hasConceptScore W2009255619C54355233 @default.

• next