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- W2009266972 abstract "Abstract Information processing, or selective dissipation, is mediated by switching elements in classical systems and by enzyme catalysis in biochemical systems. There are important differences in the character of this dissipation (from the standpoint of energy and control) in self-reproducing systems based on molecular interactions and those based on conventional computers. Conventional computers process information in a single level mode, i.e., the state of each unit of the system is accessed independently. This includes the manipulable memory units which store the computer program. In contrast, molecular self-reproducing systems process information in a hierarchical mode, based on the fact of hierarchy in molecular structure. In particular, the enzyme is described genetically at the primary level of structure (amino acid sequence) but functions at the higher, tertiary level on the basis of the interactions of many manipulable units. As a consequence it is not possible to program a biochemical system in any conventional sense. However, this is compensated by an increased capacity for accumulating appropriate information through evolution by variation and natural selection. This is possible because systems operating in the hierarchical mode are amenable to gradual modification of function. The degree of gradualness is itself an evolved property of biological molecules." @default.
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- W2009266972 title "Information processing in molecular systems" @default.
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- W2009266972 doi "https://doi.org/10.1016/0303-2647(72)90011-1" @default.
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