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• W2009280015 abstract "Abstract To improve our understanding of the organization and regulation of the wheat (Triticum aestivum) gene space, we established a transcription map of a wheat chromosome (3B) by hybridizing a newly developed wheat expression microarray with bacterial artificial chromosome pools from a new version of the 3B physical map as well as with cDNA probes derived from 15 RNA samples. Mapping data for almost 3,000 genes showed that the gene space spans the whole chromosome 3B with a 2-fold increase of gene density toward the telomeres due to an increase in the number of genes in islands. Comparative analyses with rice (Oryza sativa) and Brachypodium distachyon revealed that these gene islands are composed mainly of genes likely originating from interchromosomal gene duplications. Gene Ontology and expression profile analyses for the 3,000 genes located along the chromosome revealed that the gene islands are enriched significantly in genes sharing the same function or expression profile, thereby suggesting that genes in islands acquired shared regulation during evolution. Only a small fraction of these clusters of cofunctional and coexpressed genes was conserved with rice and B. distachyon, indicating a recent origin. Finally, genes with the same expression profiles in remote islands (coregulation islands) were identified suggesting long-distance regulation of gene expression along the chromosomes in wheat." @default.
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• W2009280015 date "2011-10-27" @default.
• W2009280015 modified "2023-10-18" @default.
• W2009280015 title "A 3,000-Loci Transcription Map of Chromosome 3B Unravels the Structural and Functional Features of Gene Islands in Hexaploid Wheat " @default.
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• W2009280015 doi "https://doi.org/10.1104/pp.111.183921" @default.
• W2009280015 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3327205" @default.
• W2009280015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22034626" @default.
• W2009280015 hasPublicationYear "2011" @default.
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