FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009294883> ?p ?o ?g. }

• W2009294883 endingPage "598" @default.
• W2009294883 startingPage "593" @default.
• W2009294883 abstract "Previous reports have shown that the biochemical activity of heparanase is significantly correlated with the invasion and metastasis of malignant cells in vitro. Recently, it was found that the human heparanase gene was cloned and highly expressed in malignant cell lines and human solid malignant tumors. In the present study, we investigated the heparanase mRNA expression by using in situ hybridization in 116 paraffin-embedded tissues of primary gastric carcinomas. To explore its clinicopathologic significance, it was detected in the various steps of tumor progression and then compared with prognostic indicators. As a result, the heparanase expression was more prevalent in late-stage rather than early-stage carcinomas (P <.0001) and was more frequent in tumors of large size (P =.0212). Expression also correlated with lymphatic (P =.0086) and venous (P =.0171) invasion and with negative prognostic factors such as lymph nodal (P <.0001) and distant (P =.0221) metastases. However, in a multivariate analysis, messenger RNA expression of heparanase was not an independent prognostic factor. It was concluded that heparanase might play an important role in the development of invasion and metastasis of the gastric cancer. It was indicated that patients with heparanase-positive gastric carcinoma would have a greater chance of metastasis with a poor prognosis." @default.
• W2009294883 created "2016-06-24" @default.
• W2009294883 creator A5004211331 @default.
• W2009294883 creator A5019033812 @default.
• W2009294883 creator A5035890737 @default.
• W2009294883 creator A5036190749 @default.
• W2009294883 creator A5046312206 @default.
• W2009294883 creator A5059584902 @default.
• W2009294883 creator A5068902273 @default.
• W2009294883 creator A5079071996 @default.
• W2009294883 creator A5085752212 @default.
• W2009294883 creator A5091121710 @default.
• W2009294883 creator A5091184577 @default.
• W2009294883 date "2002-06-01" @default.
• W2009294883 modified "2023-10-11" @default.
• W2009294883 title "Heparanase: A Key Enzyme in Invasion and Metastasis of Gastric Carcinoma" @default.
• W2009294883 cites W1485554020 @default.
• W2009294883 cites W1491748226 @default.
• W2009294883 cites W1513452909 @default.
• W2009294883 cites W1526312778 @default.
• W2009294883 cites W1585634067 @default.
• W2009294883 cites W1950519844 @default.
• W2009294883 cites W1954547860 @default.
• W2009294883 cites W1979175683 @default.
• W2009294883 cites W1999904750 @default.
• W2009294883 cites W2011158867 @default.
• W2009294883 cites W2027789202 @default.
• W2009294883 cites W2034713890 @default.
• W2009294883 cites W2039343797 @default.
• W2009294883 cites W2062606014 @default.
• W2009294883 cites W2074260855 @default.
• W2009294883 cites W2091857312 @default.
• W2009294883 cites W2092889119 @default.
• W2009294883 cites W2093454357 @default.
• W2009294883 cites W2104947013 @default.
• W2009294883 cites W2123838476 @default.
• W2009294883 cites W4251144546 @default.
• W2009294883 cites W4376596386 @default.
• W2009294883 doi "https://doi.org/10.1038/modpathol.3880571" @default.
• W2009294883 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12065771" @default.
• W2009294883 hasPublicationYear "2002" @default.
• W2009294883 type Work @default.
• W2009294883 sameAs 2009294883 @default.
• W2009294883 citedByCount "94" @default.
• W2009294883 countsByYear W20092948832012 @default.
• W2009294883 countsByYear W20092948832013 @default.
• W2009294883 countsByYear W20092948832014 @default.
• W2009294883 countsByYear W20092948832015 @default.
• W2009294883 countsByYear W20092948832016 @default.
• W2009294883 countsByYear W20092948832017 @default.
• W2009294883 countsByYear W20092948832018 @default.
• W2009294883 countsByYear W20092948832020 @default.
• W2009294883 countsByYear W20092948832021 @default.
• W2009294883 countsByYear W20092948832022 @default.
• W2009294883 countsByYear W20092948832023 @default.
• W2009294883 crossrefType "journal-article" @default.
• W2009294883 hasAuthorship W2009294883A5004211331 @default.
• W2009294883 hasAuthorship W2009294883A5019033812 @default.
• W2009294883 hasAuthorship W2009294883A5035890737 @default.
• W2009294883 hasAuthorship W2009294883A5036190749 @default.
• W2009294883 hasAuthorship W2009294883A5046312206 @default.
• W2009294883 hasAuthorship W2009294883A5059584902 @default.
• W2009294883 hasAuthorship W2009294883A5068902273 @default.
• W2009294883 hasAuthorship W2009294883A5079071996 @default.
• W2009294883 hasAuthorship W2009294883A5085752212 @default.
• W2009294883 hasAuthorship W2009294883A5091121710 @default.
• W2009294883 hasAuthorship W2009294883A5091184577 @default.
• W2009294883 hasBestOaLocation W20092948831 @default.
• W2009294883 hasConcept C121608353 @default.
• W2009294883 hasConcept C126322002 @default.
• W2009294883 hasConcept C142724271 @default.
• W2009294883 hasConcept C146357865 @default.
• W2009294883 hasConcept C151730666 @default.
• W2009294883 hasConcept C2777478136 @default.
• W2009294883 hasConcept C2777546739 @default.
• W2009294883 hasConcept C2778740770 @default.
• W2009294883 hasConcept C2779013556 @default.
• W2009294883 hasConcept C2779720271 @default.
• W2009294883 hasConcept C2780091936 @default.
• W2009294883 hasConcept C502942594 @default.
• W2009294883 hasConcept C71924100 @default.
• W2009294883 hasConcept C86803240 @default.
• W2009294883 hasConceptScore W2009294883C121608353 @default.
• W2009294883 hasConceptScore W2009294883C126322002 @default.
• W2009294883 hasConceptScore W2009294883C142724271 @default.
• W2009294883 hasConceptScore W2009294883C146357865 @default.
• W2009294883 hasConceptScore W2009294883C151730666 @default.
• W2009294883 hasConceptScore W2009294883C2777478136 @default.
• W2009294883 hasConceptScore W2009294883C2777546739 @default.
• W2009294883 hasConceptScore W2009294883C2778740770 @default.
• W2009294883 hasConceptScore W2009294883C2779013556 @default.
• W2009294883 hasConceptScore W2009294883C2779720271 @default.
• W2009294883 hasConceptScore W2009294883C2780091936 @default.
• W2009294883 hasConceptScore W2009294883C502942594 @default.
• W2009294883 hasConceptScore W2009294883C71924100 @default.
• W2009294883 hasConceptScore W2009294883C86803240 @default.
• W2009294883 hasIssue "6" @default.
• W2009294883 hasLocation W20092948831 @default.

• next