Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009305435> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2009305435 endingPage "105" @default.
- W2009305435 startingPage "96" @default.
- W2009305435 abstract "This analysis was undertaken to reduce uncertainty in acute inhalation risk assessment for mild acute effects. Applying uncertainty factors (UFs) to the no-observed-adverse-effect level (NOAEL) is the primary approach used in threshold-based risk assessments. When a NOAEL is unavailable, a UF of 10 is often applied to a lowest-observed-adverse-effect level (LOAEL) to estimate the NOAEL. We evaluated the LOAEL-to-NOAEL relationship for mild acute inhalation toxicity for 215 data sets for 36 hazardous air pollutants. The LOAEL-to-NOAEL ratios were 2.0, 5.0, 6.3, and 10.0 for the 50th, 90th, 95th, and 99 th percentile, respectively. The 90% confidence interval for the 95th percentile was 5.0-7.5. Consequently, based on previous dose placement practice, the LOAEL-to-NOAEL UF of 6 would be protective for 95% of the responses, and a value of 10 would be protective of 99% of the responses. The ratio values were not associated with the size of the experimental group. There was little variability among species, particularly at the median. This analysis is reflective only of mild acute inhalation toxicity. For other exposure routes, exposure durations, or more severe toxicity, the distributions are likely to be different." @default.
- W2009305435 created "2016-06-24" @default.
- W2009305435 creator A5074904792 @default.
- W2009305435 creator A5075214033 @default.
- W2009305435 creator A5075953837 @default.
- W2009305435 creator A5076677879 @default.
- W2009305435 date "2002-08-01" @default.
- W2009305435 modified "2023-10-18" @default.
- W2009305435 title "Characterization of the LOAEL-to-NOAEL Uncertainty Factor for Mild Adverse Effects from Acute Inhalation Exposures" @default.
- W2009305435 cites W1968345710 @default.
- W2009305435 cites W1970584496 @default.
- W2009305435 cites W1974837616 @default.
- W2009305435 cites W1975436708 @default.
- W2009305435 cites W2023485216 @default.
- W2009305435 cites W2049875817 @default.
- W2009305435 cites W2062478757 @default.
- W2009305435 cites W2063690345 @default.
- W2009305435 cites W2067252236 @default.
- W2009305435 cites W2138633646 @default.
- W2009305435 cites W2156060206 @default.
- W2009305435 cites W4249134503 @default.
- W2009305435 cites W4252135823 @default.
- W2009305435 cites W4294809574 @default.
- W2009305435 doi "https://doi.org/10.1006/rtph.2002.1562" @default.
- W2009305435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12383722" @default.
- W2009305435 hasPublicationYear "2002" @default.
- W2009305435 type Work @default.
- W2009305435 sameAs 2009305435 @default.
- W2009305435 citedByCount "50" @default.
- W2009305435 countsByYear W20093054352012 @default.
- W2009305435 countsByYear W20093054352013 @default.
- W2009305435 countsByYear W20093054352014 @default.
- W2009305435 countsByYear W20093054352015 @default.
- W2009305435 countsByYear W20093054352016 @default.
- W2009305435 countsByYear W20093054352018 @default.
- W2009305435 countsByYear W20093054352020 @default.
- W2009305435 countsByYear W20093054352021 @default.
- W2009305435 countsByYear W20093054352022 @default.
- W2009305435 countsByYear W20093054352023 @default.
- W2009305435 crossrefType "journal-article" @default.
- W2009305435 hasAuthorship W2009305435A5074904792 @default.
- W2009305435 hasAuthorship W2009305435A5075214033 @default.
- W2009305435 hasAuthorship W2009305435A5075953837 @default.
- W2009305435 hasAuthorship W2009305435A5076677879 @default.
- W2009305435 hasConcept C105795698 @default.
- W2009305435 hasConcept C116263406 @default.
- W2009305435 hasConcept C12174686 @default.
- W2009305435 hasConcept C122048520 @default.
- W2009305435 hasConcept C126322002 @default.
- W2009305435 hasConcept C2776954882 @default.
- W2009305435 hasConcept C2777495288 @default.
- W2009305435 hasConcept C29730261 @default.
- W2009305435 hasConcept C33070731 @default.
- W2009305435 hasConcept C33923547 @default.
- W2009305435 hasConcept C38652104 @default.
- W2009305435 hasConcept C41008148 @default.
- W2009305435 hasConcept C42219234 @default.
- W2009305435 hasConcept C44249647 @default.
- W2009305435 hasConcept C51671895 @default.
- W2009305435 hasConcept C71924100 @default.
- W2009305435 hasConcept C86803240 @default.
- W2009305435 hasConceptScore W2009305435C105795698 @default.
- W2009305435 hasConceptScore W2009305435C116263406 @default.
- W2009305435 hasConceptScore W2009305435C12174686 @default.
- W2009305435 hasConceptScore W2009305435C122048520 @default.
- W2009305435 hasConceptScore W2009305435C126322002 @default.
- W2009305435 hasConceptScore W2009305435C2776954882 @default.
- W2009305435 hasConceptScore W2009305435C2777495288 @default.
- W2009305435 hasConceptScore W2009305435C29730261 @default.
- W2009305435 hasConceptScore W2009305435C33070731 @default.
- W2009305435 hasConceptScore W2009305435C33923547 @default.
- W2009305435 hasConceptScore W2009305435C38652104 @default.
- W2009305435 hasConceptScore W2009305435C41008148 @default.
- W2009305435 hasConceptScore W2009305435C42219234 @default.
- W2009305435 hasConceptScore W2009305435C44249647 @default.
- W2009305435 hasConceptScore W2009305435C51671895 @default.
- W2009305435 hasConceptScore W2009305435C71924100 @default.
- W2009305435 hasConceptScore W2009305435C86803240 @default.
- W2009305435 hasIssue "1" @default.
- W2009305435 hasLocation W20093054351 @default.
- W2009305435 hasLocation W20093054352 @default.
- W2009305435 hasOpenAccess W2009305435 @default.
- W2009305435 hasPrimaryLocation W20093054351 @default.
- W2009305435 hasRelatedWork W1561318938 @default.
- W2009305435 hasRelatedWork W1974786073 @default.
- W2009305435 hasRelatedWork W1997243604 @default.
- W2009305435 hasRelatedWork W2009305435 @default.
- W2009305435 hasRelatedWork W2076331815 @default.
- W2009305435 hasRelatedWork W2077838225 @default.
- W2009305435 hasRelatedWork W2341735886 @default.
- W2009305435 hasRelatedWork W2490610372 @default.
- W2009305435 hasRelatedWork W3139121871 @default.
- W2009305435 hasRelatedWork W4220745454 @default.
- W2009305435 hasVolume "36" @default.
- W2009305435 isParatext "false" @default.
- W2009305435 isRetracted "false" @default.
- W2009305435 magId "2009305435" @default.
- W2009305435 workType "article" @default.