Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009320417> ?p ?o ?g. }
- W2009320417 endingPage "17" @default.
- W2009320417 startingPage "11" @default.
- W2009320417 abstract "To clarify the biological significance of [18F]fluorodeoxyglucose (18F-FDG) accumulation in patients with cancer, we assessed the relationships between 18F-FDG uptake and glucose transporter-1 (GLUT-1) expression and proliferation rate in human glioma and lung cancer. We obtained FDG PET images and measured standardized uptake values (SUVs) of primary tumours in 13 patients with brain glioma and 25 patients with non-small-cell lung cancer. After surgery, portions of respected tumours were obtained, and the proliferation rate was measured as proliferation index (per cent of (S+G2+M)/(G0+G1+S+G2+M)) using DNA flow cytometry. The expression of GLUT-1 in a tumour was evaluated by using immunostaining. We classified GLUT-1 expression as grade 0 (no positive cell), grade 1 (< 10% cells positive), grade 2 (11-50% cells positive) and grade 3 (51-100% cells positive). Based on the expression of GLUT-1, cases with grades 0, 1, 2 and 3 showed SUVs of 6.1 +/- 2.8, 5.0 +/- 3.2, 8.3 +/- 3.3 and 10.4 +/- 6.6, respectively (P < 0.05). Non-small-cell lung cancer showed higher FDG uptake (SUV, 8.5 +/- 5.1) and higher GLUT-1 expression (grade, 2.0 +/- 1.0) than did brain glioma (SUV, 4.7 +/- 2.5; grade, 0.8 +/- 0.8). Based on the total number of cases, SUVs did not relate to proliferation index (r = 0.19). In non-small-cell lung cancer, SUVs did not correlate with proliferation index, whereas in glioma, SUVs were strongly related to proliferation index (r = 0.79, P < 0.01). In conclusion, FDG uptake generally correlated with GLUT-1 expression in non-small-cell lung cancer and glioma. In the case of glioma, FDG uptake also indicated increased cellular proliferation, which was not demonstrated in non-small-cell lung cancer." @default.
- W2009320417 created "2016-06-24" @default.
- W2009320417 creator A5006647009 @default.
- W2009320417 creator A5013823756 @default.
- W2009320417 creator A5018851584 @default.
- W2009320417 creator A5046877593 @default.
- W2009320417 creator A5066151567 @default.
- W2009320417 creator A5091627292 @default.
- W2009320417 date "2004-01-01" @default.
- W2009320417 modified "2023-10-09" @default.
- W2009320417 title "Comparison of [18F]fluorodeoxyglucose uptake with glucose transporter-1 expression and proliferation rate in human glioma and non-small-cell lung cancer" @default.
- W2009320417 cites W1522571942 @default.
- W2009320417 cites W1542691236 @default.
- W2009320417 cites W1798641031 @default.
- W2009320417 cites W1981079102 @default.
- W2009320417 cites W1986811094 @default.
- W2009320417 cites W1993327591 @default.
- W2009320417 cites W2006619626 @default.
- W2009320417 cites W2012576700 @default.
- W2009320417 cites W2031504305 @default.
- W2009320417 cites W2060654701 @default.
- W2009320417 cites W2067829451 @default.
- W2009320417 cites W2068658980 @default.
- W2009320417 cites W2074661927 @default.
- W2009320417 cites W2077019827 @default.
- W2009320417 cites W2084918576 @default.
- W2009320417 cites W2093473761 @default.
- W2009320417 cites W2096428903 @default.
- W2009320417 cites W2126486896 @default.
- W2009320417 cites W302327703 @default.
- W2009320417 doi "https://doi.org/10.1097/00006231-200401000-00003" @default.
- W2009320417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15061260" @default.
- W2009320417 hasPublicationYear "2004" @default.
- W2009320417 type Work @default.
- W2009320417 sameAs 2009320417 @default.
- W2009320417 citedByCount "67" @default.
- W2009320417 countsByYear W20093204172012 @default.
- W2009320417 countsByYear W20093204172013 @default.
- W2009320417 countsByYear W20093204172014 @default.
- W2009320417 countsByYear W20093204172015 @default.
- W2009320417 countsByYear W20093204172016 @default.
- W2009320417 countsByYear W20093204172017 @default.
- W2009320417 countsByYear W20093204172018 @default.
- W2009320417 countsByYear W20093204172019 @default.
- W2009320417 countsByYear W20093204172020 @default.
- W2009320417 countsByYear W20093204172021 @default.
- W2009320417 countsByYear W20093204172023 @default.
- W2009320417 crossrefType "journal-article" @default.
- W2009320417 hasAuthorship W2009320417A5006647009 @default.
- W2009320417 hasAuthorship W2009320417A5013823756 @default.
- W2009320417 hasAuthorship W2009320417A5018851584 @default.
- W2009320417 hasAuthorship W2009320417A5046877593 @default.
- W2009320417 hasAuthorship W2009320417A5066151567 @default.
- W2009320417 hasAuthorship W2009320417A5091627292 @default.
- W2009320417 hasConcept C121608353 @default.
- W2009320417 hasConcept C126322002 @default.
- W2009320417 hasConcept C142724271 @default.
- W2009320417 hasConcept C1491633281 @default.
- W2009320417 hasConcept C161573976 @default.
- W2009320417 hasConcept C199374082 @default.
- W2009320417 hasConcept C203014093 @default.
- W2009320417 hasConcept C204232928 @default.
- W2009320417 hasConcept C2775842073 @default.
- W2009320417 hasConcept C2776256026 @default.
- W2009320417 hasConcept C2777415128 @default.
- W2009320417 hasConcept C2777751288 @default.
- W2009320417 hasConcept C2778227246 @default.
- W2009320417 hasConcept C2779306644 @default.
- W2009320417 hasConcept C2910938049 @default.
- W2009320417 hasConcept C2989005 @default.
- W2009320417 hasConcept C4224716 @default.
- W2009320417 hasConcept C502942594 @default.
- W2009320417 hasConcept C54355233 @default.
- W2009320417 hasConcept C553184892 @default.
- W2009320417 hasConcept C62112901 @default.
- W2009320417 hasConcept C71924100 @default.
- W2009320417 hasConcept C86803240 @default.
- W2009320417 hasConceptScore W2009320417C121608353 @default.
- W2009320417 hasConceptScore W2009320417C126322002 @default.
- W2009320417 hasConceptScore W2009320417C142724271 @default.
- W2009320417 hasConceptScore W2009320417C1491633281 @default.
- W2009320417 hasConceptScore W2009320417C161573976 @default.
- W2009320417 hasConceptScore W2009320417C199374082 @default.
- W2009320417 hasConceptScore W2009320417C203014093 @default.
- W2009320417 hasConceptScore W2009320417C204232928 @default.
- W2009320417 hasConceptScore W2009320417C2775842073 @default.
- W2009320417 hasConceptScore W2009320417C2776256026 @default.
- W2009320417 hasConceptScore W2009320417C2777415128 @default.
- W2009320417 hasConceptScore W2009320417C2777751288 @default.
- W2009320417 hasConceptScore W2009320417C2778227246 @default.
- W2009320417 hasConceptScore W2009320417C2779306644 @default.
- W2009320417 hasConceptScore W2009320417C2910938049 @default.
- W2009320417 hasConceptScore W2009320417C2989005 @default.
- W2009320417 hasConceptScore W2009320417C4224716 @default.
- W2009320417 hasConceptScore W2009320417C502942594 @default.
- W2009320417 hasConceptScore W2009320417C54355233 @default.
- W2009320417 hasConceptScore W2009320417C553184892 @default.
- W2009320417 hasConceptScore W2009320417C62112901 @default.