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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009328749> ?p ?o ?g. }

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• W2009328749 abstract "By using perfusions and bolus administration, coupled with postembedding immunocytochemical procedures, we have identified the structures involved in the transport of derivatized orosomucoid (α 1 -acidic glycoprotein) across the continuous microvascular endothelium of the murine myocardium. Our findings indicate that: ( i ) monomeric orosomucoid binds to the luminal surface of the endothelium; ( ii ) it is restricted to caveolae during its transport across the endothelium; ( iii ) it is detected in the perivascular spaces at early time points (by 1 min) and in larger quantities at later time points (>5 min) from the beginning of its perfusion or its intravascular administration; ( iv ) no orosomucoid molecules are found in the intercellular junctions or at the abluminal exits of interendothelial spaces; and ( v ) the vesicular transport of orosomucoid is strongly inhibited by N -ethylmaleimide (>80%). Because, by size and shape, the orosomucoid qualifies as a preferential probe for the postulated small pore system, our results are discussed in relation to the pore theory of capillary permeability." @default.
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• W2009328749 date "1998-05-26" @default.
• W2009328749 modified "2023-10-15" @default.
• W2009328749 title "Transcytosis of α ₁ -acidic glycoprotein in the continuous microvascular endothelium" @default.
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• W2009328749 doi "https://doi.org/10.1073/pnas.95.11.6175" @default.
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