Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009328775> ?p ?o ?g. }
- W2009328775 endingPage "60" @default.
- W2009328775 startingPage "52" @default.
- W2009328775 abstract "An increasing body of scientific research and observational evidence indicates that resting heart rate (HR) is inversely related to the lifespan among homeothermic mammals and within individual species. In numerous human studies with patients stratified by resting HR, increased HR is universally associated with greater risk of death. The correlation between HR and maximum lifespan seems to be due to both basal metabolic rate and cardiovascular-related mortality risk. Both intrinsic and extrinsic factors are already postulated to determine how the biological clock works, through regulating and modulating the processes such as protein oxidation, free radical production, inflammation and telomere shortening. Given the remarkable correlation between HR and lifespan, resting HR should be seriously considered as another possible cap on maximum lifespan. Future research is needed to determine whether deliberate cardiac slowing, through methods like lifestyle modification, pharmacological intervention, or medical devices, can decelerate biological clock of aging, reduce cardiovascular mortality and increase maximum lifespan in humans in general." @default.
- W2009328775 created "2016-06-24" @default.
- W2009328775 creator A5003825798 @default.
- W2009328775 creator A5039044513 @default.
- W2009328775 date "2009-01-01" @default.
- W2009328775 modified "2023-10-16" @default.
- W2009328775 title "Heart rate, lifespan, and mortality risk" @default.
- W2009328775 cites W109337650 @default.
- W2009328775 cites W1819087145 @default.
- W2009328775 cites W1901983160 @default.
- W2009328775 cites W1960974308 @default.
- W2009328775 cites W1965832441 @default.
- W2009328775 cites W1966893077 @default.
- W2009328775 cites W1967340565 @default.
- W2009328775 cites W1968096578 @default.
- W2009328775 cites W1968684702 @default.
- W2009328775 cites W1972130746 @default.
- W2009328775 cites W1972545707 @default.
- W2009328775 cites W1973874135 @default.
- W2009328775 cites W1974195141 @default.
- W2009328775 cites W1978277438 @default.
- W2009328775 cites W1980874812 @default.
- W2009328775 cites W1983582745 @default.
- W2009328775 cites W1987894901 @default.
- W2009328775 cites W1991460472 @default.
- W2009328775 cites W1995421025 @default.
- W2009328775 cites W1997979241 @default.
- W2009328775 cites W2000037288 @default.
- W2009328775 cites W2002064924 @default.
- W2009328775 cites W2003658404 @default.
- W2009328775 cites W2004904888 @default.
- W2009328775 cites W2006570946 @default.
- W2009328775 cites W2007710159 @default.
- W2009328775 cites W2010152131 @default.
- W2009328775 cites W2010396034 @default.
- W2009328775 cites W2012729997 @default.
- W2009328775 cites W2012737132 @default.
- W2009328775 cites W2012833408 @default.
- W2009328775 cites W2012969618 @default.
- W2009328775 cites W2014717126 @default.
- W2009328775 cites W2016958976 @default.
- W2009328775 cites W2021941221 @default.
- W2009328775 cites W2025674512 @default.
- W2009328775 cites W2027390876 @default.
- W2009328775 cites W2029949795 @default.
- W2009328775 cites W2033065807 @default.
- W2009328775 cites W2041816612 @default.
- W2009328775 cites W2043523583 @default.
- W2009328775 cites W2045350116 @default.
- W2009328775 cites W2046746746 @default.
- W2009328775 cites W2046851561 @default.
- W2009328775 cites W2052482212 @default.
- W2009328775 cites W2053379890 @default.
- W2009328775 cites W2055893971 @default.
- W2009328775 cites W2056991918 @default.
- W2009328775 cites W2057566353 @default.
- W2009328775 cites W2061520159 @default.
- W2009328775 cites W2065599062 @default.
- W2009328775 cites W2068884498 @default.
- W2009328775 cites W2069368135 @default.
- W2009328775 cites W2087706354 @default.
- W2009328775 cites W2090128860 @default.
- W2009328775 cites W2090586799 @default.
- W2009328775 cites W2096114109 @default.
- W2009328775 cites W2098523076 @default.
- W2009328775 cites W2100907438 @default.
- W2009328775 cites W2102948895 @default.
- W2009328775 cites W2106203125 @default.
- W2009328775 cites W2108955518 @default.
- W2009328775 cites W2110642608 @default.
- W2009328775 cites W2118392285 @default.
- W2009328775 cites W2125702693 @default.
- W2009328775 cites W2129413040 @default.
- W2009328775 cites W2131408584 @default.
- W2009328775 cites W2133217116 @default.
- W2009328775 cites W2137330513 @default.
- W2009328775 cites W2140983593 @default.
- W2009328775 cites W2143996615 @default.
- W2009328775 cites W2145466024 @default.
- W2009328775 cites W2148685655 @default.
- W2009328775 cites W2158771665 @default.
- W2009328775 cites W2158987804 @default.
- W2009328775 cites W2159957110 @default.
- W2009328775 cites W2163161539 @default.
- W2009328775 cites W2164912716 @default.
- W2009328775 cites W2167279654 @default.
- W2009328775 cites W2168238404 @default.
- W2009328775 cites W2169601419 @default.
- W2009328775 cites W2169948001 @default.
- W2009328775 cites W2170138349 @default.
- W2009328775 cites W2170445507 @default.
- W2009328775 cites W2172090944 @default.
- W2009328775 cites W2271861937 @default.
- W2009328775 cites W2319955501 @default.
- W2009328775 cites W2326508838 @default.
- W2009328775 cites W2340324006 @default.
- W2009328775 cites W2727581825 @default.
- W2009328775 cites W4242869084 @default.