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• W2009332598 abstract "Chronic hepatitis C virus infection in children and adolescents: Epidemiology, natural history, and assessment of the safety and efficacy of combination therapy Giuseppe Indolfi, Elisa Bartolini, Davide Casavola, Massimo RestiDepartment of Sciences for Women and Child’s Health, Liver and Pediatric Unit, Anna Meyer Children’s Hospital, University of Florence, Florence, ItalyAbstract: Hepatitis C virus (HCV) is the most common cause of chronic liver disease of infectious etiology in children. Most of the children infected with HCV are asymptomatic, and only a few of them develop signs and symptoms of end-stage liver disease early in life. It is not possible to predict either in which patients HCV infection will have a bad outcome or the critical time in early adulthood when disease progression will accelerate. The experiences with therapy in children with chronic hepatitis C are based on earlier and continuing data from adult trials. The currently recommended treatment for chronic HCV infection in adults is the combination of peginterferon-a and ribavirin. The choice of this regimen is based on the results of randomized clinical trials that demonstrated the superiority of this combination treatment over standard interferon-a and ribavirin. Recently, results of pivotal, multicenter, interventional open-label studies on combined treatment with peginterferon-a and ribavirin in children have been published, and the US Food and Drug Administration and the European Medicines Agency have approved the combination therapy in those older than 3 years. The aim of this review is to evaluate critically the available data regarding the safety and efficacy of combination treatment with peginterferon-a and ribavirin in children.Keywords: treatment, peginterferon, ribavirin, adverse events, sustained viral response" @default.
• W2009332598 created "2016-06-24" @default.
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• W2009332598 date "2010-10-01" @default.
• W2009332598 modified "2023-09-29" @default.
• W2009332598 title "Chronic hepatitis C virus infection in children and adolescents: Epidemiology, natural history, and assessment of the safety and efficacy of combination therapy" @default.
• W2009332598 cites W1525292740 @default.
• W2009332598 cites W1547384224 @default.
• W2009332598 cites W1967229580 @default.
• W2009332598 cites W1969030917 @default.
• W2009332598 cites W1970300761 @default.
• W2009332598 cites W1971011563 @default.
• W2009332598 cites W1972889983 @default.
• W2009332598 cites W1976626343 @default.
• W2009332598 cites W1977024529 @default.
• W2009332598 cites W1977085586 @default.
• W2009332598 cites W1977294239 @default.
• W2009332598 cites W1977681680 @default.
• W2009332598 cites W1978121135 @default.
• W2009332598 cites W1979146353 @default.
• W2009332598 cites W1987371523 @default.
• W2009332598 cites W1987699550 @default.
• W2009332598 cites W1988171027 @default.
• W2009332598 cites W1989033233 @default.
• W2009332598 cites W1993187347 @default.
• W2009332598 cites W1995507674 @default.
• W2009332598 cites W1998494653 @default.
• W2009332598 cites W2002060878 @default.
• W2009332598 cites W2002515752 @default.
• W2009332598 cites W2004053209 @default.
• W2009332598 cites W2006309458 @default.
• W2009332598 cites W2010179567 @default.
• W2009332598 cites W2017726794 @default.
• W2009332598 cites W2019296444 @default.
• W2009332598 cites W2027476072 @default.
• W2009332598 cites W2036550935 @default.
• W2009332598 cites W2037555620 @default.
• W2009332598 cites W2039857559 @default.
• W2009332598 cites W2040785319 @default.
• W2009332598 cites W2042191290 @default.
• W2009332598 cites W2046096648 @default.
• W2009332598 cites W2047295508 @default.
• W2009332598 cites W2049872768 @default.
• W2009332598 cites W2054850951 @default.
• W2009332598 cites W2055613616 @default.
• W2009332598 cites W2057558823 @default.
• W2009332598 cites W2058001273 @default.
• W2009332598 cites W2061709969 @default.
• W2009332598 cites W2063503814 @default.
• W2009332598 cites W2064129992 @default.
• W2009332598 cites W2064590565 @default.
• W2009332598 cites W2064696362 @default.
• W2009332598 cites W2065631609 @default.
• W2009332598 cites W2066124462 @default.
• W2009332598 cites W2071607535 @default.
• W2009332598 cites W2072474042 @default.
• W2009332598 cites W2078232024 @default.
• W2009332598 cites W2087088974 @default.
• W2009332598 cites W2087304793 @default.
• W2009332598 cites W2096861652 @default.
• W2009332598 cites W2103370354 @default.
• W2009332598 cites W2110816492 @default.
• W2009332598 cites W2113864802 @default.
• W2009332598 cites W2116296213 @default.
• W2009332598 cites W2122987848 @default.
• W2009332598 cites W2142329259 @default.
• W2009332598 cites W2143681435 @default.
• W2009332598 cites W2145129522 @default.
• W2009332598 cites W2149004771 @default.
• W2009332598 cites W2155349044 @default.
• W2009332598 cites W2155992852 @default.
• W2009332598 cites W2158566694 @default.
• W2009332598 cites W2159183335 @default.
• W2009332598 cites W2164890008 @default.
• W2009332598 cites W2170098167 @default.
• W2009332598 cites W2170750446 @default.
• W2009332598 cites W2297070282 @default.
• W2009332598 cites W2317713562 @default.
• W2009332598 cites W2322434219 @default.
• W2009332598 cites W2331780769 @default.
• W2009332598 cites W2412717352 @default.
• W2009332598 cites W255235625 @default.
• W2009332598 cites W3140139051 @default.
• W2009332598 cites W61361935 @default.
• W2009332598 cites W82010554 @default.
• W2009332598 doi "https://doi.org/10.2147/ahmt.s6750" @default.
• W2009332598 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3915892" @default.
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