Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009334906> ?p ?o ?g. }
Showing items 1 to 39 of
39
with 100 items per page.
- W2009334906 endingPage "S28" @default.
- W2009334906 startingPage "S28" @default.
- W2009334906 abstract "indicated that the strain NDM-1-Saitama belonged to sequence type ST42 which had not been reported previously. Complete sequencing and gap closing by PCR demonstrated a 49,441bp IncFII plasmid which bears 53 genes. The plasmid pNDM-1Saitama consists of 22kb backbone and 27kb multi-drug resistant region. Half of the backbone showed 100% perfect match of the sequence ofK. pneumoniae plasmid pKP048which contains blaKPC-2. The second half of the backbone has only partial similarity to the plasmids with blaNDM-1 and blaCTX-M3. The multi-drug resistant region of pNDM-1-Saitama contains 13 drug resistant elements including blaNDM-1, bleMBL, blaDHA-1, sul1, armA, mel, and mph2. The complete sequence of an ISAba125 insertion sequence in the upstream of the blaNDM-1 gene suggests horizontal transfer of the blaNDM-1 gene between Enterobacteriaceae and Acinetobacter . The possible recombination events between NDM-1 plasmids and plasmids carrying KPC and CTXM-3 or A. baumannii genome are suggested. The blaNDM-1 gene is always followed by the bleomycin resistant protein gene bleMBL. The blaNDM-1bleMBL elements are followed either by blaDHA-1 and ampR or molecular chaperones groES and groER. Our study suggests community-acquired blaNDM-1 plasmid has undergone frequent recombination with plasmids carrying other clinically important resistance genes KPC and CTX-M-3." @default.
- W2009334906 created "2016-06-24" @default.
- W2009334906 creator A5018636224 @default.
- W2009334906 date "2013-06-01" @default.
- W2009334906 modified "2023-09-24" @default.
- W2009334906 title "SP23-3 Characterization of NDM-1" @default.
- W2009334906 doi "https://doi.org/10.1016/s0924-8579(13)70204-8" @default.
- W2009334906 hasPublicationYear "2013" @default.
- W2009334906 type Work @default.
- W2009334906 sameAs 2009334906 @default.
- W2009334906 citedByCount "0" @default.
- W2009334906 crossrefType "journal-article" @default.
- W2009334906 hasAuthorship W2009334906A5018636224 @default.
- W2009334906 hasConcept C171250308 @default.
- W2009334906 hasConcept C192562407 @default.
- W2009334906 hasConcept C2780841128 @default.
- W2009334906 hasConceptScore W2009334906C171250308 @default.
- W2009334906 hasConceptScore W2009334906C192562407 @default.
- W2009334906 hasConceptScore W2009334906C2780841128 @default.
- W2009334906 hasLocation W20093349061 @default.
- W2009334906 hasOpenAccess W2009334906 @default.
- W2009334906 hasPrimaryLocation W20093349061 @default.
- W2009334906 hasRelatedWork W1982108276 @default.
- W2009334906 hasRelatedWork W2009883749 @default.
- W2009334906 hasRelatedWork W2027794350 @default.
- W2009334906 hasRelatedWork W2129021616 @default.
- W2009334906 hasRelatedWork W29442446 @default.
- W2009334906 hasRelatedWork W330727063 @default.
- W2009334906 hasRelatedWork W4226186049 @default.
- W2009334906 hasRelatedWork W4235541336 @default.
- W2009334906 hasRelatedWork W651098627 @default.
- W2009334906 hasRelatedWork W2945461732 @default.
- W2009334906 hasVolume "42" @default.
- W2009334906 isParatext "false" @default.
- W2009334906 isRetracted "false" @default.
- W2009334906 magId "2009334906" @default.
- W2009334906 workType "article" @default.