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- W2009347673 abstract "Although the specific profiling of endogenous glycopeptides in serum is highly inclined towards the discovery of disease biomarkers, studies on the endogenous glycopeptides (glycopeptidome) have never been conducted because of several factors. These factors include the high dynamic range of serum proteins, the inadequacy of traditional sample preparation techniques in proteomics for low-molecular-weight (LMW) proteins, and the relatively low abundances of glycopeptides. Boronic acid-functionalized mesoporous silica was synthesized in this study to overcome the limitations of the state-of-the-art methods for glycopeptidome research. The boronic acid-functionalized mesoporous silica exhibited excellent selectivity by analyzing glycopeptides in the mixture of glycopeptides/non-glycopeptides at molar ratio of 1:100, extreme sensitivity (the limit of detection was at the fmol level), good binding capacity (40 mg g−1), as well as the high post-enrichment recovery of glycopeptides (up to 88.10%). The as-prepared material possessing both glycopeptide-suitable pore size and glycopeptide-specific selectivity has shown special capability for enriching the endogenous glycopeptides. Fifteen unique glycosylation sites mapped to 15 different endogenous glycopeptides were identified in rat serum. The established protocol revealed for the first time the rat serum glycopeptidome." @default.
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- W2009347673 date "2012-11-01" @default.
- W2009347673 modified "2023-10-07" @default.
- W2009347673 title "Highly specific revelation of rat serum glycopeptidome by boronic acid-functionalized mesoporous silica" @default.
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- W2009347673 cites W2004458374 @default.
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- W2009347673 cites W2027451973 @default.
- W2009347673 cites W2032604597 @default.
- W2009347673 cites W2039315788 @default.
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- W2009347673 doi "https://doi.org/10.1016/j.aca.2012.10.002" @default.
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