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- W2009356745 abstract "We prospectively assessed the risk of second relapse in 192 patients with clinically isolated syndromes (CIS) divided into three groups: patients lacking oligoclonal IgG bands (OC-IgG, 25.7%), those showing OC-IgG (52.4%), and those with both OC-IgG and lipid-specific IgM bands (LS-OC-IgM, 22%). OC-IgG increased 9.3-fold the risk compared to lacking OC-IgG; OC-IgG+LS-OC-IgM increased the risk 39.6-fold compared to not having OC-IgG and 4.4-fold compared to having only OC-IgG. Median time to second relapse was 0.7 years for patients with OC-IgG+LS-OC-IgM and 3.3 years for those with only OC-IgG. Therefore, CSF analysis identifies CIS patients at risk of second relapse." @default.
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- W2009356745 date "2010-09-14" @default.
- W2009356745 modified "2023-10-17" @default.
- W2009356745 title "The risk of relapse after a clinically isolated syndrome is related to the pattern of oligoclonal bands" @default.
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- W2009356745 doi "https://doi.org/10.1016/j.jneuroim.2010.05.032" @default.
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