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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009371489> ?p ?o ?g. }

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• W2009371489 abstract "A large scale process for the synthesis of HIV protease inhibitor candidate ABT-378 has been developed which utilizes an intermediate common to the synthesis of ritonavir, Abbott's first generation compound. The synthesis relies on the sequential acylation of this intermediate which is carried through as a mixture of diastereomers until the penultimate step. A synthesis of acid 5, derived from l-valine, is also reported." @default.
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• W2009371489 date "2000-05-27" @default.
• W2009371489 modified "2023-10-16" @default.
• W2009371489 title "Synthesis of HIV Protease Inhibitor ABT-378 (Lopinavir)" @default.
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• W2009371489 doi "https://doi.org/10.1021/op990202j" @default.
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