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• W2009385144 abstract "Triacylglycerol secretion rates were studied in high-sucrose-fed rabbits in order to understand the effect of exogenous cholesterol on the serum triacylglycerol levels. Four groups of male rabbits were fed for 16 days as follows: Group 1, rabbit chow (basal); Group 2, chow + 1 mg/kcal cholesterol; Group 3, high sucrose (76% of calories); Group 4, high sucrose + 1 mg/kcal cholesterol. TGSR was measured in fasting animals by intravenous injection of Triton WR 1339. The fasting TG level in Group 4 was 49% lower than that in Group 3 (P < 0.001). Among the dietary groups TGSR was lowest in sucrose with cholesterol group (P < 0.001). Exogenous cholesterol increased the VLDL total protein (pre-Triton) in chow-fed animals by 65% while it decreasd the same by 30% in sucrose-fed animals. The newly secreted VLDL (post-Triton) in the cholesterol-supplemented sucrose diet group had less triacylglycerol and ApoB relative to cholesterol. We suggest that dietary cholesterol results in the secretion of relatively triacylglycerol-poor and cholesterol-rich VLDL at a reduced rate in high sucrose-fed rabbits." @default.
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• W2009385144 date "1980-08-01" @default.
• W2009385144 modified "2023-10-18" @default.
• W2009385144 title "Decreased secretion of triacylglycerol by exogenous cholesterol in high sucrose-fed rabbits" @default.
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• W2009385144 doi "https://doi.org/10.1016/0006-2944(80)90087-3" @default.
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