FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009398977> ?p ?o ?g. }

• W2009398977 endingPage "827" @default.
• W2009398977 startingPage "818" @default.
• W2009398977 abstract "Abstract— Benzoporphyrin derivative monoacid ring A (BPD-MA), a chlorin-type molecule, is a new photosensitizer currently in phase II clinical trials for the treatment by pho-todynamic therapy of cancerous lesions, psoriasis and pathologic neovascularization. The photochemistry (type I and/or II) of BPD-MA has been studied in homogeneous solution and in aqueous dispersions of unilamellar liposomes of dipalmitoylphosphatidylcholine (DPPC) using electron paramagnetic resonance and spectrophotometric methods. When oxygen-saturated solutions of BPD-MA were illuminated with 690 nm light, singlet oxygen (1O2), superoxide anion radical (O2−), hydroxyl radical (OH) and hydrogen peroxide (H2O2) were formed. The BPD-MA generates 1O2 with a quantum yield of ca 0.81 in ethanolic solution. The quantum yield does not change upon incorporation of BPD-MA into liposomes of DPPC. The superoxide anion radical was generated by the BPD-MA anion radical (BPD-MA−) via electron transfer to oxygen, and this process was significantly enhanced by the presence of electron donors. The rate of production of 02 was also dependent on the concentration of BPD-MA used (3-100 μM). The quantum yield of O2−was found to be 0.011 and 0.025 in aqueous solution and DPPC liposomes, respectively. Moreover, O2_upon dis-proportionation can generate H2O2 and ultimately the highly reactive OH via the Fenton reaction. In anaerobic homogeneous solution, BPD-MA−was predominantly photoproduced via the self-electron transfer between the excited- and ground-state species. The presence of an electron donor significantly promotes the reduced form of BPD-MA. These findings suggest that the photodynamic action of BPD-MA may proceed via both type I and type II mechanisms." @default.
• W2009398977 created "2016-06-24" @default.
• W2009398977 creator A5010493249 @default.
• W2009398977 creator A5050560452 @default.
• W2009398977 creator A5087442210 @default.
• W2009398977 creator A5088926356 @default.
• W2009398977 date "1997-05-01" @default.
• W2009398977 modified "2023-09-30" @default.
• W2009398977 title "EPR and Spectrophotometric Studies of Free Radicals (O₂°⁻, °OH, BPD-MA°⁻) and Singlet Oxygen (¹O₂) Generated by Irradiation of Benzoporphyrin Derivative Monoacid Ring A" @default.
• W2009398977 cites W1553328291 @default.
• W2009398977 cites W1967274113 @default.
• W2009398977 cites W1968955935 @default.
• W2009398977 cites W1972098136 @default.
• W2009398977 cites W1973703868 @default.
• W2009398977 cites W1975199730 @default.
• W2009398977 cites W1982857351 @default.
• W2009398977 cites W1994715798 @default.
• W2009398977 cites W1996575997 @default.
• W2009398977 cites W1997295076 @default.
• W2009398977 cites W2002769318 @default.
• W2009398977 cites W2005740213 @default.
• W2009398977 cites W2008433356 @default.
• W2009398977 cites W2013440635 @default.
• W2009398977 cites W2025340493 @default.
• W2009398977 cites W2025647998 @default.
• W2009398977 cites W2026598069 @default.
• W2009398977 cites W2026849188 @default.
• W2009398977 cites W2028245407 @default.
• W2009398977 cites W2039800094 @default.
• W2009398977 cites W2040870649 @default.
• W2009398977 cites W2042117072 @default.
• W2009398977 cites W2044342015 @default.
• W2009398977 cites W2045120677 @default.
• W2009398977 cites W2064450459 @default.
• W2009398977 cites W2065930100 @default.
• W2009398977 cites W2070686079 @default.
• W2009398977 cites W2073424837 @default.
• W2009398977 cites W2084343059 @default.
• W2009398977 cites W2088728854 @default.
• W2009398977 cites W2091210609 @default.
• W2009398977 cites W2101036832 @default.
• W2009398977 cites W2101942483 @default.
• W2009398977 cites W2116144604 @default.
• W2009398977 cites W2141504031 @default.
• W2009398977 cites W2144401284 @default.
• W2009398977 cites W2158599884 @default.
• W2009398977 cites W2183385134 @default.
• W2009398977 cites W2524604160 @default.
• W2009398977 cites W3011668247 @default.
• W2009398977 cites W4211077226 @default.
• W2009398977 cites W4244547059 @default.
• W2009398977 doi "https://doi.org/10.1111/j.1751-1097.1997.tb01929.x" @default.
• W2009398977 hasPublicationYear "1997" @default.
• W2009398977 type Work @default.
• W2009398977 sameAs 2009398977 @default.
• W2009398977 citedByCount "37" @default.
• W2009398977 countsByYear W20093989772013 @default.
• W2009398977 countsByYear W20093989772018 @default.
• W2009398977 countsByYear W20093989772022 @default.
• W2009398977 countsByYear W20093989772023 @default.
• W2009398977 crossrefType "journal-article" @default.
• W2009398977 hasAuthorship W2009398977A5010493249 @default.
• W2009398977 hasAuthorship W2009398977A5050560452 @default.
• W2009398977 hasAuthorship W2009398977A5087442210 @default.
• W2009398977 hasAuthorship W2009398977A5088926356 @default.
• W2009398977 hasConcept C121332964 @default.
• W2009398977 hasConcept C123669783 @default.
• W2009398977 hasConcept C139066938 @default.
• W2009398977 hasConcept C147789679 @default.
• W2009398977 hasConcept C171001562 @default.
• W2009398977 hasConcept C178790620 @default.
• W2009398977 hasConcept C181199279 @default.
• W2009398977 hasConcept C181500209 @default.
• W2009398977 hasConcept C184651966 @default.
• W2009398977 hasConcept C185544564 @default.
• W2009398977 hasConcept C185592680 @default.
• W2009398977 hasConcept C187961010 @default.
• W2009398977 hasConcept C2776778087 @default.
• W2009398977 hasConcept C2777516457 @default.
• W2009398977 hasConcept C2780795997 @default.
• W2009398977 hasConcept C33062035 @default.
• W2009398977 hasConcept C46141821 @default.
• W2009398977 hasConcept C540031477 @default.
• W2009398977 hasConcept C62520636 @default.
• W2009398977 hasConcept C75473681 @default.
• W2009398977 hasConcept C91881484 @default.
• W2009398977 hasConceptScore W2009398977C121332964 @default.
• W2009398977 hasConceptScore W2009398977C123669783 @default.
• W2009398977 hasConceptScore W2009398977C139066938 @default.
• W2009398977 hasConceptScore W2009398977C147789679 @default.
• W2009398977 hasConceptScore W2009398977C171001562 @default.
• W2009398977 hasConceptScore W2009398977C178790620 @default.
• W2009398977 hasConceptScore W2009398977C181199279 @default.
• W2009398977 hasConceptScore W2009398977C181500209 @default.
• W2009398977 hasConceptScore W2009398977C184651966 @default.
• W2009398977 hasConceptScore W2009398977C185544564 @default.
• W2009398977 hasConceptScore W2009398977C185592680 @default.
• W2009398977 hasConceptScore W2009398977C187961010 @default.

• next