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- W2009421489 abstract "This editorial refers to ‘Potential impact of myocardial perfusion scintigraphy as gatekeeper for invasive examination and treatment in patients with stable angina pectoris: observational study without post-test referral bias’† by P.F. Hoilund-Carlsen et al ., on page 29 Myocardial perfusion scintigraphy (MPS) is an effective and cost-effective technique in patients presenting with stable chest pain. It provides a reliable assessment of coronary obstruction leading to inducible perfusion abnormalities and of the prognosis of disease. It can therefore be used both for diagnosis and for triage of patients between initial medical therapy and invasive investigation with a view to revascularization. It is recommended as the first-line diagnostic procedure when exercise electrocardiography is difficult or inconclusive, such as when the resting ECG is abnormal, when maximal dynamic exercise is unlikely to be achieved, and in women.1 Although comparison between a test of coronary function and coronary anatomy is fraught with difficulties, the sensitivity of MPS for detecting angiographic stenosis is 85–90% and the normal MPS rate in a low likelihood population (normalcy) is 90–95%, depending upon the population studied.2 As with any diagnostic test, MPS is most useful in patients with an intermediate (25–75%) likelihood of underlying coronary disease, but its prognostic value also makes it helpful in patients with a high likelihood. It is diagnostically least useful in patients with a low likelihood of disease in whom performing any diagnostic test can be questioned, although a normal scan reliably indicates a risk of myocardial infarction or cardiac death below 1% per year for up to 5 or even 10 years depending upon risk factors.Coronary angiography has historically been used as the gold standard for the diagnosis of coronary disease although as an anatomical test it does not … *Corresponding author. E-mail address : r.underwood{at}imperial.ac.uk" @default.
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- W2009421489 title "Myocardial perfusion scintigraphy: an important step between clinical assessment and coronary angiography in patients with stable chest painThe opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology." @default.
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- W2009421489 doi "https://doi.org/10.1093/eurheartj/ehi627" @default.
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