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- W2009449767 abstract "Flow cytofluorimetric methods have been used to quantitate the interaction between a divalent monoclonal antibody and a tumour cell surface antigen. After standardization using fluorescein and 125I-labelled antibodies, kinetics of association and dissociation were measured, and antibody bound at equilibrium quantitated. A mathematical model was developed in conjunction with these experimental results which allowed the calculation of rates for monovalent association and monovalent and divalent dissociation, and a description of the contribution of each to the level of bound antibody at different antibody concns." @default.
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- W2009449767 date "1985-01-01" @default.
- W2009449767 modified "2023-09-27" @default.
- W2009449767 title "Kinetics of divalent monoclonal antibody binding to tumour cell surface antigens using flow cytometry: Standardization and mathematical analysis" @default.
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- W2009449767 doi "https://doi.org/10.1016/0161-5890(85)90029-x" @default.
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